ReviewClinical ophthalmology (Auckland, N.Z.)2016
Ectasia risk factors in refractive surgery.
Review in Clinical ophthalmology (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03708575 (Risk Assessment for Corneal Ectasia Following Laser in Situ Keratomileusis), which is not on this map. Cited by 62 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Assessment for Corneal Ectasia Following Laser in Situ Keratomileusis
Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 142 citations in OpenAlex.
- Corneal biomechanical properties after SMILE versus FLEX, LASIK, LASEK, or PRK: a systematic review and meta-analysis.BMC ophthalmology · 2019Pooled it
- Femtosecond laser-assisted in situ keratomileusis with topography-guided or asphericity-adjusted derived data: a comparative contralateral eye study.BMC ophthalmology · 2022Trial
- One-Year Efficacy and Safety of Combined Photorefractive Keratectomy and Accelerated Corneal Collagen Cross-Linking after Intacs SK Intracorneal Ring Segment Implantation in Moderate Keratoconus.BioMed research international · 2019Trial
- Combination of tissue-derived and shape-based parameters for subclinical keratoconus detection.Biomedical optics express · 2026Article
- Comparative analysis of 70 SMILE and 70 toric ICL eyes for myopic oblique astigmatism: a matched cohort study from an initial pool of 11,929 eyes.International ophthalmology · 2026Article
- The Impact of Small Incision Lenticule Extraction on the Biomechanical Properties of the Cornea: A Review.Bioengineering (Basel, Switzerland) · 2025Review
- Deep learning-based keratoconus detection from Scheimpflug images.Biomedical optics express · 2025Article
- Article
- Asymmetric Presentation of Corneal Ectasia With Acute Hydrops 34 Years Following Bilateral Radial Keratotomy.Cureus · 2025Article
- The effect of preoperative total antioxidant capacity on short-term outcomes after kerato-lenticule extraction surgery.Scientific reports · 2025Article
- Early assessment of visual outcomes and corneal stability in eyes with a pre-planned residual stromal thickness of 280 to 300 µm following small incision lenticule extraction.International journal of ophthalmology · 2025Article
- Comparison of Anterion, MS-39, Pentacam, and Sirius in Corneal Assessment Prior to Refractive Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Unraveling the impact of laser refractive surgery on corneal ectasia: anFrontiers in bioengineering and biotechnology · 2025Article
- Influence of Biometric and Corneal Tomographic Parameters on Normative Corneal Aberrations Measured by Root Mean Square.Journal of clinical medicine · 2024Article
- Early elastic and viscoelastic corneal biomechanical changes after photorefractive keratectomy and small incision lenticule extraction.International ophthalmology · 2024Article
- Factors associated with changes in posterior corneal surface following laser-assisted in situ keratomileusis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Transepithelial Photorefractive Keratectomy-Review.Vision (Basel, Switzerland) · 2024Review
- Corneal Collagen Crosslinking for Ectasia After Refractive Surgery: A Systematic Review and Meta-Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Corneal topography in preterm children aged 2 years to 12 years with or without retinopathy of prematurity.Eye (London, England) · 2023Article
- Normative Topographic Anterior and Posterior Corneal Astigmatism: Axis Distribution and Its Relations with Ocular and Biometric Parameters.Journal of clinical medicine · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review outlines risk factors of post-laser in situ keratomileusis (LASIK) ectasia that can be detected preoperatively and presents a new metric to be considered in the detection of ectasia risk. Relevant factors in refractive surgery screening include the analysis of intrinsic biomechanical properties (information obtained from corneal topography/tomography and patient's age), as well as the analysis of alterable biomechanical properties (information obtained from the amount of tissue altered by surgery and the remaining load-bearing tissue). Corneal topography patterns of placido disk seem to play a pivotal role as a surrogate of corneal strength, and abnormal corneal topography remains to be the most important identifiable risk factor for ectasia. Information derived from tomography, such as pachymetric and epithelial maps as well as computational strategies, to help in the detection of keratoconus is additional and relevant. High percentage of tissue altered (PTA) is the most robust risk factor for ectasia after LASIK in patients with normal preoperative corneal topography. Compared to specific residual stromal bed (RSB) or central corneal thickness values, percentage of tissue altered likely provides a more individualized measure of biomechanical alteration because it considers the relationship between thickness, tissue altered through ablation and flap creation, and ultimate RSB thickness. Other recognized risk factors include low RSB, thin cornea, and high myopia. Age is also a very important risk factor and still remains as one of the most overlooked ones. A comprehensive screening approach with the Ectasia Risk Score System, which evaluates multiple risk factors simultaneously, is also a helpful tool in the screening strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.