ReviewCold Spring Harbor perspectives in medicine2016
Interventions for Human Frailty: Physical Activity as a Model.
Review in Cold Spring Harbor perspectives in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 113 citations in OpenAlex.
- Longitudinal associations of chronic pain and sleep quality with frailty progression in community-dwelling older adults.Aging clinical and experimental research · 2026Article
- Acid-Base Dysregulation Links Aging Metabolism to Frailty.Aging cell · 2026Article
- The effect of long-term adherence to physical activity recommendations in midlife on plasma proteins associated with frailty in the Atherosclerosis Risk in Communities (ARIC) study.European journal of epidemiology · 2026Article
- Analysis of exercise behavior and influencing factors in patients with inflammatory bowel disease during remission and mild disease activity.BMC gastroenterology · 2025Article
- Chronic diseases and frailty transitions in community-dwelling older adults: evidence from a national longitudinal cohort study.BMC geriatrics · 2025Article
- Association between perceived neighborhood environment, sedentary behavior, walking, and moderate-to-vigorous physical activity and frailty: an isotemporal substitution model.BMC geriatrics · 2025Article
- Combined association between dietary inflammatory index-related dietary patterns and physical activity with frailty in Chinese older adults: findings from a cross-sectional.Frontiers in public health · 2025Article
- The Effect of Young People-Assisted, Individualized, Motion-Based Video Games on Physical, Cognitive, and Social Frailty Among Community-Dwelling Older Adults With Frailty: Randomized Controlled Trial.JMIR serious games · 2024Article
- Metabolic dysfunction and the development of physical frailty: an aging war of attrition.GeroScience · 2024Review
- Reliability, validity and minimal detectable change of the Chinese Version of the Assessment of Physical Activity in Frail Older People (APAFOP-C).BMC geriatrics · 2024Article
- Clinical Application of Frailty in the Evaluation of Solid Organ Transplant Patients.Current transplantation reports · 2024Article
- Cross-sectional associations between patterns and composition of upright and stepping events with physical function: insights from The Maastricht Study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024Article
- Metabolomic characterization of vigor to frailty among community-dwelling older Black and White men and women.GeroScience · 2024Article
- Decreased mitochondrial respiration associates with frailty in community-dwelling older adults.Frontiers in cell and developmental biology · 2024Article
- Associations between device-measured physical activity and performance-based physical function outcomes in adults: a systematic review and meta-analysis.BMJ public health · 2023Review
- Muscle power predicts frailty status over four years: A retrospective cohort study of the National Health and Aging Trends Study.Journal of frailty, sarcopenia and falls · 2023Article
- Gender Differences in Determinants of the Components of the Frailty Phenotype among Older Adults in India: Findings from LASI Wave-1.International journal of environmental research and public health · 2023Article
- Review
- Associations between Frailty and Ambient Temperature in Winter: Findings from a Population-Based Study.International journal of environmental research and public health · 2022Article
- Machine learning models for identifying pre-frailty in community dwelling older adults.BMC geriatrics · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last 100 years, populations in developed countries have experienced an unprecedented addition of 30 years to life expectancy. Developing countries are now experiencing this same phenomenon, but over a shorter time frame. With this success comes the challenge of maximizing health and vitality across these added years. The compression of morbidity to the latest point in the human life span could unleash a sustained third demographic dividend that benefits all of society. To accomplish this, society needs to invest in the prevention and treatment of frailty, as well as in the prevention of chronic diseases at every age and stage of life. A model intervention, physical activity, may offer a road map.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.