ArticleJournal of biomedical optics2016
In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Rapid peripheral reprogramming of myelinated afferents drives human hyperalgesia.bioRxiv : the preprint server for biology · 2026Article
- What do we know about the epidermis' optical properties and their influence on optical device functionality?Biophotonics discovery · 2025Review
- Mapping cutaneous field carcinogenesis of nonmelanoma skin cancer using mesoscopic imaging of pro-inflammation cues.Experimental dermatology · 2024Review
- Influence of optical aberrations on depth-specific spatial frequency domain techniques.Journal of biomedical optics · 2022Article
- Quantifying the confounding effect of pigmentation on measured skin tissue optical properties: a comparison of colorimetry with spatial frequency domain imaging.Journal of biomedical optics · 2022Article
- Melanins as Sustainable Resources for Advanced Biotechnological Applications.Global challenges (Hoboken, NJ) · 2021Review
- Dual-DMD hyperspectral spatial frequency domain imaging (SFDI) using dispersed broadband illumination with a demonstration of blood stain spectral monitoring.Biomedical optics express · 2021Article
- An Iterative method to quantify epidermal melanin concentration using Spatial Frequency Domain Imaging and a layered Monte Carlo model.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- A paintable phosphorescent bandage for postoperative tissue oxygen assessment in DIEP flap reconstruction.Science advances · 2020Article
- The influence of morphological distribution of melanin on parameter selection in laser thermotherapy for vascular skin diseases.Lasers in medical science · 2020Article
- Quantifying skin photodamage with spatial frequency domain imaging: statistical results.Biomedical optics express · 2019Article
- Review of structured light in diffuse optical imaging.Journal of biomedical optics · 2018Review
- Method using in vivo quantitative spectroscopy to guide design and optimization of low-cost, compact clinical imaging devices: emulation and evaluation of multispectral imaging systems.Journal of biomedical optics · 2018Article
- Portable (handheld) clinical device for quantitative spectroscopy of skin, utilizing spatial frequency domain reflectance techniques.The Review of scientific instruments · 2017Article
- Noninvasive mesoscopic imaging of actinic skin damage using spatial frequency domain imaging.Biomedical optics express · 2017Article
- Compressed single pixel imaging in the spatial frequency domain.Journal of biomedical optics · 2017Article
- Separating melanin from hemodynamics in nevi using multimode hyperspectral dermoscopy and spatial frequency domain spectroscopy.Journal of biomedical optics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Skin is a highly structured tissue, raising concerns as to whether skin pigmentation due to epidermal melanin may confound accurate measurements of underlying hemodynamics. Using both venous and arterial cuff occlusions as a means of inducing differential hemodynamic perturbations, we present analyses of spectra limited to the visible or near-infrared regime, in addition to a layered model approach. The influence of melanin, spanning Fitzpatrick skin types I to V, on underlying estimations of hemodynamics in skin as interpreted by these spectral regions are assessed. The layered model provides minimal cross-talk between melanin and hemodynamics and enables removal of problematic correlations between measured tissue oxygenation estimates and skin phototype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.