Evidence map›Paper›PMID 27143433›Full record

ArticleNeurobiology of aging2016

The relationships between age, associative memory performance, and the neural correlates of successful associative memory encoding.

Marianne de Chastelaine, Julia T Mattson, Tracy H Wang, Brian E Donley, Michael D Rugg

Abstract read
In one paragraph

Article in Neurobiology of aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  7. Dissociative Effects of Age on Neural Differentiation at the Category and Item Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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  12. Prediction in the Aging Brain: Merging Cognitive, Neurological, and Evolutionary Perspectives.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  13. Article
  14. The Retrieval-Related Anterior Shift Is Moderated by Age and Correlates with Memory Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
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  15. Article
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  18. Early-life education may help bolster declarative memory in old age, especially for women.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marianne de ChastelaineCenter for Vital Longevity and School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA. Electronic address: mad106120@utdallas.edu.
Julia T MattsonUT Southwestern Medical Center, Dallas, TX, USA.
Tracy H WangCenter for Vital Longevity and School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA.
Brian E DonleyCenter for Vital Longevity and School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA.
Michael D RuggCenter for Vital Longevity and School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA.

Funding

Relationship Between Neural Correlates of Episodic Memory,Age, Memory PerformancR01AG039103 · NIA · UNIVERSITY OF TEXAS DALLAS · PI RUGG, MICHAEL D · 2011 to 2015
$1.5M
NIA NIH HHS R01 AG039103
6 · The paper itself

Abstract

Using functional magnetic resonance imaging, subsequent memory effects (greater activity for later remembered than later forgotten study items) predictive of associative encoding were compared across samples of young, middle-aged, and older adults (total N = 136). During scanning, participants studied visually presented word pairs. In a later test phase, they discriminated between studied pairs, "rearranged" pairs (items studied on different trials), and new pairs. Subsequent memory effects were identified by contrasting activity elicited by study pairs that went on to be correctly judged intact or incorrectly judged rearranged. Effects in the hippocampus were age-invariant and positively correlated across participants with associative memory performance. Subsequent memory effects in the right inferior frontal gyrus (IFG) were greater in the older than the young group. In older participants only, both left and, in contrast to prior reports, right IFG subsequent memory effects correlated positively with memory performance. We suggest that the IFG is especially vulnerable to age-related decline in functional integrity and that the relationship between encoding-related activity in right IFG and memory performance depends on the experimental context.

Indexed as

AdolescentAdultAgedAgingFemaleHippocampusHumansMagnetic Resonance ImagingMaleMemoryMemory, EpisodicMiddle AgedNeuropsychological TestsRecognition, PsychologyRecruitment, NeurophysiologicalYoung AdultAgingAssociative recognitionEpisodic memoryfMRIHippocampusOver-recruitment

Identifiers

PMID27143433
PMCPMC4857153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.