Evidence map›Paper›PMID 27142943›Full record

ArticleImmunology and cell biology2016

Modeling the dynamics of neonatal CD8

Arnold Reynaldi, Norah L Smith, Timothy E Schlub, Vanessa Venturi, Brian D Rudd, Miles P Davenport

Open access · greenAbstract read
In one paragraph

Article in Immunology and cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Perturbation of the Preterm Human Immune System in Early Life.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Early-life human CD8Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Neonatal T Cells: A Reinterpretation.Annual review of immunology · 2020
    Review
  16. Cutting Edge: Elevated Glycolytic Metabolism Limits the Formation of Memory CD8Journal of immunology (Baltimore, Md. : 1950) · 2019
    Article
  17. Article
  18. Article
  19. Cord Blood CD8Frontiers in immunology · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Arnold ReynaldiInfection Analytics Program, Kirby Institute for Infection and Immunity, UNSW Australia, Sydney, New South Wales, Australia.
Norah L SmithDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.
Timothy E SchlubSchool of Public Health, Faculty of Medicine, The University of Sydney, Sydney, New South Wales, Australia.
Vanessa VenturiInfection Analytics Program, Kirby Institute for Infection and Immunity, UNSW Australia, Sydney, New South Wales, Australia.
Brian D RuddDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.
Miles P DavenportInfection Analytics Program, Kirby Institute for Infection and Immunity, UNSW Australia, Sydney, New South Wales, Australia.
Institute of Infection and Immunity · CACornell University · USUNSW Sydney · AU

Funding

Research Resource for Human Organs and Tissues (U42)U42OD011158 · OD · NATIONAL DISEASE RESEARCH INTERCHANGE · PI BELL, THOMAS J · 2012 to 2025
$25.0M
The developmental layers in the CD8+ T cell response to chronic infectionR01AI110613 · NIAID · CORNELL UNIVERSITY · PI GRIMSON, ANDREW W, RUDD, BRIAN DAVID · 2014 to 2022
$4.1M
Mechanisms Limiting Neonatal ImmunityR01AI105265 · NIAID · CORNELL UNIVERSITY · PI RUDD, BRIAN DAVID · 2014 to 2023
$4.0M
NIAID NIH HHS R01 AI105265NIAID NIH HHS R01 AI110613NIH HHS U42 OD011158
6 · The paper itself

Abstract

Neonates are particularly susceptible to a number of infections, and the neonatal CD8

Indexed as

Models, ImmunologicalAdolescentAdoptive TransferAdultAnimalsCD8-Positive T-LymphocytesCell DifferentiationCell DivisionCell ProliferationFetal BloodHumansImmunologic MemoryInfant, NewbornKineticsMaleMice

Identifiers

PMID27142943
PMCPMC5069106
OpenAlexW2345421503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.