Evidence map›Paper›PMID 27142623›Full record

ArticleWorld journal of surgery2016

Perioperative Blood Transfusion is Associated with an Increased Mortality in Older Surgical Patients.

Cristina Roque-Castellano, Joaquín Marchena-Gómez, Roberto Fariña-Castro, María Asunción Acosta-Mérida, María Desirée Armas-Ojeda, María Isabel Sánchez-Guédez

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05605860 (Development of a Predictive Algorithm for a Hemoglobin Value of Less Than 10 g/dl Postoperatively in Scheduled Hip or Knee Arthroplasty), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05605860 completednot on this mapstarted 2022, after this paper: background citation

Development of a Predictive Algorithm for a Hemoglobin Value of Less Than 10 g/dl Postoperatively in Scheduled Hip or Knee Arthroplasty

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2022 to 2023Enrolled1,041ConditionsHip Prosthetic Surgery, Knee Prosthetic Surgery
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina Roque-CastellanoDepartment of General Surgery, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain.
Joaquín Marchena-GómezDepartment of General Surgery, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain. jmargom@telefonica.net.
Roberto Fariña-CastroDepartment of Anesthesiology, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain.
María Asunción Acosta-MéridaDepartment of General Surgery, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain.
María Desirée Armas-OjedaDepartment of General Surgery, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain.
María Isabel Sánchez-GuédezDepartment of General Surgery, Hospital Universitario de Gran Canaria Dr. Negrín, Barranco La Ballena s/n, Las Palmas de Gran Canaria, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMore surgical interventions are being performed on octogenarian patients. The aim of this study was to identify factors associated with operative mortality and to determine if perioperative transfusions could affect mortality outcomes in a nonselected series of octogenarian patients undergoing surgery.

methodsA descriptive cross-sectional study was performed on a population of 413 consecutive patients over 80 years old, treated surgically, and divided into two groups: transfused and nontransfused patients. The following variables were recorded: sociodemographic characteristics, main diagnoses, surgical procedure and its characteristics, ASA score, Charlson comorbidity index (CCI), National Nosocomial Infection Surveillance (NNIS) index, transfusion requirements, the Clavien-Dindo classification of surgical complications, and operative mortality.

resultsThe mean age of the patients was 84.5 years (SD + 3.6). Transfused (25.2 %) and nontransfused patients had similar characteristics; except for neoplasia (P <0.001), NNIS (P = 0.008), operative mortality (P = 0.004), and complications according to Clavien-Dindo score (P <0.001). Operative mortality was 20.1 % (83 patients). The predictive variables associated with operative mortality were ASA score (P <0.001), emergency surgery (P <0.001), and blood transfusion (P = 0.004). After adjusting for the variables age, ASA class, NNIS, emergency surgery, and neoplasia, the multivariate analysis showed that the perioperative transfusion in octogenarian patients continued to be significantly associated with operative mortality (P = 0.019; OR 1.97, 95 % CI 1.12-3.47).

conclusionPerioperative transfusion is an independent predictor of postoperative mortality in surgical octogenarian patients.

Indexed as

Transfusion ReactionAdultAgedAged, 80 and overAge FactorsBlood TransfusionCross InfectionCross-Sectional StudiesFemaleHumansMaleMiddle AgedMultivariate AnalysisPerioperative CarePostoperative PeriodRisk Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.