ReviewClinical rheumatology2016
Myocardial ischemia as presenting manifestation of IgG4-related disease: a case-based review.
Review in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Clinical characteristics and multimodal imaging insights of coronary involvement in immunoglobulin G4-related disease.Frontiers in immunology · 2025Pooled it
- Immunoglobulin G4-related coronary periarteritis: a systematic literature review with a case series.Clinical rheumatology · 2022Pooled it
- Pulmonary vascular involvement of IgG4-related disease: Case series with a PRISMA-compliant systemic review.Medicine · 2019Pooled it
- Successful rituximab treatment in IgG4-related coronary periarteritis: a case-based review.Rheumatology international · 2024Review
- IgG4-related disease involving coronary and pulmonary arteries: a case report and literature review.Cardiovascular diagnosis and therapy · 2023Article
- Coronary artery ectasia associated with IgG4-related disease: a case report and literature review.BMC cardiovascular disorders · 2023Review
- Intracoronary IgG4-related disease as an unusual cause of sudden cardiac arrest: a case series.European heart journal. Case reports · 2022Article
- Sudden unexpected death due to coronary thrombosis associated with isolated necrotizing vasculitis in the coronary arteries of a young adult.Forensic science, medicine, and pathology · 2019Article
- The Utility of FDG PET/CT in IgG4-Related Disease with a Focus on Coronary Artery Involvement.Nuclear medicine and molecular imaging · 2018Article
- Immunoglobulin G4-Related Cardiovascular Diseases.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary involvement in IgG4-related disease (IgG4-RD) has been scarcely reported, and myocardial ischemia as its presenting feature is even rarer. Here, we describe an additional case with novel and relevant observations. The patient was a previously healthy, middle-aged woman who presented to the clinic with new-onset typical angina. One tumefactive lesion encasing the left anterior descending artery was found during her workup. The most common underlying malignancies with secondary cardiac involvement were rationally ruled out. Symptoms persisted despite medical treatment, and she was therefore referred to surgery. Tumor excision was successfully performed, and she received coronary bypass grafting. IgG4-related coronary arteritis with pseudotumor formation was subsequently diagnosed following the comprehensive diagnostic criteria. This condition was clinically classified as active and circulating plasmablasts were found to be increased (5480/mL), even when these were determined 38 days after surgery. A PET/CT revealed an additional hypermetabolic lymph node. She was therefore treated with rituximab as induction therapy (two 1000 mg doses, administered 15 days apart). Three months later, her disease remained clinically inactive. Circulating plasmablasts were repeated and these had dropped to 0/mL. We thereafter review the current and pertinent literature on the topic, emphasizing the previous cases with similar presenting features (n = 7). We lastly suggest that IgG4-RD should be part of the differential diagnosis of any patient with tumefactive lesions surrounding the coronary arteries, since it can initially presented as sudden cardiac death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.