ArticleCritical care (London, England)2016
Identification of regional overdistension, recruitment and cyclic alveolar collapse with electrical impedance tomography in an experimental ARDS model.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05024500 (Clinical, Respiratory, Peripheral, Muscle and Functionality Outcomes of Adult ICU Inpatients and Rehabilitation-center Outpatients With COVID-19), which is not on this map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical, Respiratory, Peripheral, Muscle and Functionality Outcomes of Adult ICU Inpatients and Rehabilitation-center Outpatients With COVID-19
Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Personalized positive end-expiratory pressure in spontaneously breathing patients with acute respiratory distress syndrome by simultaneous electrical impedance tomography and transpulmonary pressure monitoring: a randomized crossover trial.Intensive care medicine · 2024Trial
- Determinants of tidal recruitment/derecruitment assessed by electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients.American journal of respiratory and critical care medicine · 2026Article
- Enhancing tidal volume estimation from electrical impedance tomography (EIT) by applying human anthropometric information.Journal of clinical monitoring and computing · 2026Article
- When mechanical power remains high despite conventional lung-protective settings: a physiology-driven bedside framework.Annals of intensive care · 2026Review
- Preterm infants on high-frequency oscillatory ventilation: electrical impedance tomography during lung recruitment.Pediatric research · 2025Observational
- Imaging in animal models: bridging experimental findings and human pathophysiology.Critical care (London, England) · 2025Review
- Thoracic Electric Impedance Tomography Detects Lung Volume Changes in Amyotrophic Lateral Sclerosis.Muscle & nerve · 2025Article
- A novel positive end-expiratory pressure titration using electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients on mechanical ventilation: an observational study from the MaastrICCht cohort.Journal of clinical monitoring and computing · 2025Observational
- The potential risk of ventilator-induced lung injury from five different PEEP titration techniques in ARDS.Frontiers in medicine · 2025Article
- Imaging the Lung in ARDS: A Primer.Respiratory care · 2024Review
- Regional peak flow as a novel approach to assess regional pulmonary mechanics by electrical impedance tomography: an observational validation study.Annals of translational medicine · 2023Article
- Effect of Position Change From the Bed to a Wheelchair on the Regional Ventilation Distribution Assessed by Electrical Impedance Tomography in Patients With Respiratory Failure.Frontiers in medicine · 2021Article
- First Attempt at Using Electrical Impedance Tomography to Predict High Flow Nasal Cannula Therapy Outcomes at an Early Phase.Frontiers in medicine · 2021Article
- Optimal mean airway pressure during high-frequency oscillatory ventilation in an experimental model of acute respiratory distress syndrome: EIT-based method.Annals of intensive care · 2020Article
- Effect of postextubation high-flow nasal cannula therapy on lung recruitment and overdistension in high-risk patient.Critical care (London, England) · 2020Article
- Mechanical Ventilation Guided by Electrical Impedance Tomography in Children With Acute Lung Injury.Critical care explorations · 2019Article
- Lung monitoring with electrical impedance tomography: technical considerations and clinical applications.Journal of thoracic disease · 2019Review
- Clinical Scenarios of the Application of Electrical Impedance Tomography in Paediatric Intensive Care.Scientific reports · 2019Article
- Positive end-expiratory pressure titration with electrical impedance tomography and pressure-volume curve in severe acute respiratory distress syndrome.Annals of intensive care · 2019Article
- Mechanical ventilation guided by electrical impedance tomography in pediatric acute respiratory distress syndrome.Journal of clinical monitoring and computing · 2018Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInformation on regional ventilation distribution in mechanically ventilated patients is important to develop lung protective ventilation strategies. In the present prospective animal study, we introduce an electrical impedance tomography (EIT)-based method to classify lungs into normally ventilated, overinflated, tidally recruited/derecruited and recruited regions.
methodsAcute respiratory distress syndrome (ARDS) was introduced with repeated bronchoalveolar lavage in ten healthy male pigs until the ratio of arterial partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) decreased to less than 100 mmHg and remained stable for 30 minutes. Stepwise positive end-expiratory pressure (PEEP) increments were performed from 0 cmH2O to 30 cmH2O with 3 cmH2O increase every 5 minutes. Respiratory system compliance (Crs), blood gases and hemodynamics were measured at the same time. Lung regions at end-expiration and during tidal breathing were identified in EIT images.
resultsOverinflated regions contain air at end-expiration but they are not or are only minimally ventilated. Recruited regions compared to reference PEEP level contain air at end-expiration of arbitrary PEEP level but not at that of reference PEEP level. Tidally recruited/derecruited regions are not represented in lung regions at end-expiration but are ventilated during tidal breathing. The results coincided with measurements of blood gases. The coefficient for correlation between the number of recruited pixels and PaO2/FiO2 was 0.89 ± 0.12 (p = 0.02).
conclusionThe proposed novel EIT-based method provides information on overinflation, recruitment and cyclic alveolar collapse at the bedside, which may improve the ventilation strategies used.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.