Evidence map›Paper›PMID 27142032›Full record

ArticleInternational urogynecology journal2016

Fourteen-day administration of corticosterone may induce detrusor overactivity symptoms.

Andrzej Wróbel, Anna Serefko, Ewa Poleszak, Tomasz Rechberger

Open access · hybridAbstract read
In one paragraph

Article in International urogynecology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Pharmacological Management of Urinary Incontinence: Current and Emerging Treatment.Clinical pharmacology : advances and applications · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Inhibition of the CRFNaunyn-Schmiedeberg's archives of pharmacology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrzej WróbelSecond Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland. wrobelandrzej@yahoo.com.
Anna SerefkoChair and Department of Applied Pharmacy, Medical University of Lublin, Chodźki 1, 20-093, Lublin, Poland.
Ewa PoleszakChair and Department of Applied Pharmacy, Medical University of Lublin, Chodźki 1, 20-093, Lublin, Poland.
Tomasz RechbergerSecond Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisEpidemiological studies demonstrated that patients suffering from overactive bladder often present with different mental problems, amongst which depression is the most frequently observed. The main goal of our study was to check if the repeated administration of corticosterone (CORT) is able to evoke the depressive-like behaviour and detrusor overactivity (DO) symptoms in rats. Moreover, we investigated whether the acute administration of common antidepressants (imipramine, 30 mg/kg, and fluoxetine, 15 mg/kg), antimuscarinic (oxybutynin chloride, 0.5 mg/kg) or CRF

methodsThe experiments were carried out on female Wistar rats. All applied surgical and histopathology procedures, cystometric investigations, locomotor activity and forced swim measurements have been fully described in the published literature.

resultsFourteen-day administration of CORT may induce both depressive and DO symptoms in rats, which are reversed by the inhibition of CRF

conclusionsIt seems that the CRF

Indexed as

Analysis of VarianceAnimalsAntidepressive Agents, TricyclicCorticosteroneCRF Receptor, Type 1DepressionDisease Models, AnimalFemaleFluoxetineImipramineMuscarinic AntagonistsRandom AllocationRatsRats, WistarReceptors, Corticotropin-Releasing HormoneSelective Serotonin Reuptake InhibitorsAntidepressive Agents, TricyclicCorticosteroneCRF Receptor, Type 1FluoxetineImipramineMuscarinic AntagonistsReceptors, Corticotropin-Releasing HormoneSelective Serotonin Reuptake InhibitorsCorticosteroneCRF1 antagonistDepressionOveractive bladderRats

Identifiers

PMID27142032
PMCPMC5065892
OpenAlexW2347031085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.