ReviewCellular and molecular life sciences : CMLS2016
Distribution of glucan-branching enzymes among prokaryotes.
Review in Cellular and molecular life sciences : CMLS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
- Differences in Microbial Community Structure Determine the Functional Specialization of Gut Segments ofMicroorganisms · 2025Article
- The early evolution of the glycolytic pathway from autotrophic origins to glycogen and back.FEMS microbiology reviews · 2025Review
- Orthologs of Branching Enzymes from Cyanobacteria Accumulating Distinct Types of α-Glucans Share Common Reaction Product Specificity.Journal of applied glycoscience · 2025Article
- Crystal Structure and Mutational Studies of Cyanobacterial Branching Enzymes Reveal the Structural Determinants of Reaction Product Specificity.Journal of applied glycoscience · 2025Article
- Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin.Foods (Basel, Switzerland) · 2024Article
- Architecture, Function, Regulation, and Evolution of α-Glucans Metabolic Enzymes in Prokaryotes.Chemical reviews · 2024Review
- The Synergistic Effect of GH13 and GH57 GBEs ofPolymers · 2023Article
- Article
- Biochemical characteristics and potential application of a thermostable starch branching enzyme from Bacillus licheniformis.AMB Express · 2023Article
- From Prokaryotes to Eukaryotes: Insights Into the Molecular Structure of Glycogen Particles.Frontiers in molecular biosciences · 2021Review
- Article
- Structure and Evolution of Glycogen Branching Enzyme N-Termini From Bacteria.Frontiers in microbiology · 2018Article
- Functional Roles of Starch Binding Domains and Surface Binding Sites in Enzymes Involved in Starch Biosynthesis.Frontiers in plant science · 2018Review
- Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model.The Journal of biological chemistry · 2017Article
- Remarkable evolutionary relatedness among the enzymes and proteins from the α-amylase family.Cellular and molecular life sciences : CMLS · 2016Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucan-branching enzyme plays an essential role in the formation of branched polysaccharides, glycogen, and amylopectin. Only one type of branching enzyme, belonging to glycoside hydrolase family 13 (GH13), is found in eukaryotes, while two types of branching enzymes (GH13 and GH57) occur in prokaryotes (Bacteria and Archaea). Both of these types are the members of protein families containing the diverse specificities of amylolytic glycoside hydrolases. Although similarities are found in the catalytic mechanism between the two types of branching enzyme, they are highly distinct from each other in terms of amino acid sequence and tertiary structure. Branching enzymes are found in 29 out of 30 bacterial phyla and 1 out of 5 archaeal phyla, often along with glycogen synthase, suggesting the existence of α-glucan production and storage in a wide range of prokaryotes. Enormous variability is observed as to which type and how many copies of branching enzyme are present depending on the phylum and, in some cases, even among species of the same genus. Such a variation may have occurred through lateral transfer, duplication, and/or differential loss of genes coding for branching enzyme during the evolution of prokaryotes.
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Registered trials
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