Evidence map›Paper›PMID 27141839›Full record

ArticleDrug and alcohol dependence2016

Internalizing and externalizing disorders as predictors of alcohol use disorder onset during three developmental periods.

Richard F Farmer, Jeff M Gau, John R Seeley, Derek B Kosty, Kenneth J Sher, Peter M Lewinsohn

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Genetically influenced externalizing and internalizing risk pathways as novel prevention targets.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Richard F FarmerOregon Research Institute, 1776 Millrace Drive, Eugene, OR, 97403, United States. Electronic address: rfarmer@ori.org.
Jeff M GauOregon Research Institute, 1776 Millrace Drive, Eugene, OR, 97403, United States. Electronic address: jeffg@ori.org.
John R SeeleyOregon Research Institute, 1776 Millrace Drive, Eugene, OR, 97403, United States; University of Oregon, College of Education, Department of Special Education and Clinical Sciences, Eugene, OR, 97403, United States. Electronic address: jseeley@uoregon.edu.
Derek B KostyOregon Research Institute, 1776 Millrace Drive, Eugene, OR, 97403, United States. Electronic address: dkosty@ori.org.
Kenneth J SherUniversity of Missouri - Columbia, Department of Psychological Sciences, 200 South Seventh Street, Columbia, MO, 65211, United States. Electronic address: SherK@missouri.edu.
Peter M LewinsohnOregon Research Institute, 1776 Millrace Drive, Eugene, OR, 97403, United States. Electronic address: pete@ori.org.

Funding

Risk for Substance Use Disorders and Comorbid ConditionsR01DA012951 · NIDA · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 2000 to 2004
$3.3M
Alcohol and Adult Development: Understanding Etiology and ConsequencesK05AA017242 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI SHER, KENNETH JAMES · 2007 to 2016
$2.1M
Natural Course and Developmental Trajectories of Alcohol Use DisordersR01AA020968 · NIAAA · OREGON RESEARCH INSTITUTE · PI FARMER, RICHARD FRANCIS, SEELEY, JOHN R · 2012 to 2013
$406k
NATURAL HISTORY OF DEPRESSION IN ADOLESCENTSR01MH050522 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1993 to 2001
$121k
ADOLESCENT DEPRESSION: PREVALENCE &PSYCHOSOCIAL ASPECTSR01MH040501 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1986 to 1990
–
NIAAA NIH HHS K05 AA017242NIAAA NIH HHS R01 AA020968NIDA NIH HHS R01 DA012951NIMH NIH HHS R01 MH040501NIMH NIH HHS R01 MH050522
6 · The paper itself

Abstract

backgroundThe developmental pathways associated with an enhanced risk for future alcohol use disorders (AUDs) continue to be a topic of both interest and debate. In this research, internalizing and externalizing disorders were evaluated as prospective predictors of the index AUD episode onset, separately within three developmental periods: early-to-middle adolescence (age 13.0-17.9), late adolescence (18.0-20.9), and early adulthood (21.0-30.0).

methodsParticipants (N=816) were initially randomly selected from nine high schools in western Oregon and subsequently interviewed on four separate occasions between ages 16 and 30, during which current and past AUDs were assessed as well as a full range of psychiatric disorders associated with internalizing and externalizing psychopathology domains.

resultsIn adjusted analyses for each of the three developmental periods investigated, externalizing domain psychopathology from the most proximal adjoining developmental period predicted AUD onset. Distal externalizing psychopathology also predicted AUD onset among early adult onset cases. Proximal or distal internalizing psychopathology, in comparison, was not found to be a significant predictor of AUD onset in adjusted analyses for any of the developmental periods examined.

conclusionsFindings overall suggest that externalizing developmental histories are robust predictors of AUD onset within the age range during which index episodes are most likely to occur, and that gender does not moderate this association.

Indexed as

Internal-External ControlAdolescentAdultAlcohol-Related DisordersFemaleHumansMaleOregonProspective StudiesPsychopathologyRisk FactorsYoung AdultAlcohol use disorders (AUDs)ExternalizingGenderInternalizingPredictorsPsychopathology

Identifiers

PMID27141839
PMCPMC4893997

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.