Trial reportDrug and alcohol dependence2016
Individual differences in brain responses to cigarette-related cues and pleasant stimuli in young smokers.
Trial report in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Personalizing smoking cessation pharmacotherapy using neuroaffective reactivity profiles: A randomized controlled trial.Addiction (Abingdon, England) · 2026Trial
- The late positive potential predicts contingency management outcomes for cocaine use disorder.Drug and alcohol dependence · 2025Article
- Towards neuromarkers for tailored smoking cessation treatments.Addiction neuroscience · 2023Article
- Cue-reactivity targeted smoking cessation intervention in individuals with tobacco use disorder: a scoping review.Frontiers in psychiatry · 2023Article
- The reality of "food porn": Larger brain responses to food-related cues than to erotic images predict cue-induced eating.Psychophysiology · 2019Article
- Cigarette cues capture attention of smokers and never-smokers, but for different reasons.Drug and alcohol dependence · 2018Article
- Event-Related Potentials as Biomarkers of Behavior Change Mechanisms in Substance Use Disorder Treatment.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Review
- Beyond Cue Reactivity: Non-Drug-Related Motivationally Relevant Stimuli Are Necessary to Understand Reactivity to Drug-Related Cues.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundDecreased sensitivity to pleasant stimuli is associated with a higher vulnerability to nicotine dependence in youths and with difficulty quitting in adult smokers. Recently, we showed that smokers showing lower brain reactivity to non-cigarette-related pleasant images than to cigarette-related ones have lower chances of achieving long-term abstinence during a quit attempt.
methodsWe tested whether individual differences in brain responses to cigarette-related and pleasant stimuli require a long history of smoking to develop by measuring the late positive potential (LPP) to cigarette cues, emotional, and neutral stimuli in 45 young, light smokers (ages 18-25). k-means cluster analysis was used to partition smokers into two groups based on the magnitude of their LPPs.
resultsGroup 1 was characterized by larger LPPs to pleasant pictures than cigarette-related pictures whereas Group 2 showed the opposite pattern.
conclusionsOur results suggest that individual differences in brain responses to cigarette-related and pleasant cues do not require a long smoking history to develop.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.