ArticleRegenerative engineering and translational medicine2016
Multiscale Poly-(ϵ-caprolactone) Scaffold Mimicking Nonlinearity in Tendon Tissue Mechanics.
Article in Regenerative engineering and translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Optimizing strategies in tendon tissue engineering through effective scaffold design: overview of recent advancements.Regenerative medicine · 2026Review
- Beneficial Effects of Zoledronic Acid on Tendons of the Osteogenesis Imperfecta Mouse (Oim).Pharmaceuticals (Basel, Switzerland) · 2023Article
- Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair.Journal of materials science. Materials in medicine · 2022Article
- Polymer-Based Constructs for Flexor Tendon Repair: A Review.Polymers · 2022Review
- Nanofiber curvature with Rho GTPase activity increases mouse embryonic fibroblast random migration velocity.Integrative biology : quantitative biosciences from nano to macro · 2021Article
- Human mesenchymal stem cell morphology, migration, and differentiation on micro and nano-textured titanium.Bioactive materials · 2019Article
- Biofabrication of Electrospun Scaffolds for the Regeneration of Tendons and Ligaments.Materials (Basel, Switzerland) · 2018Review
- Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II: treatment options.Journal of experimental orthopaedics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Regenerative medicine plays a critical role in the future of medicine. However, challenges remain to balance stem cells, biomaterial scaffolds, and biochemical factors to create successful and effective scaffold designs. This project analyzes scaffold architecture with respect to mechanical capability and preliminary mesenchymal stem cell response for tendon regeneration. An electrospun fiber scaffold with tailorable properties based on a "Chinese-fingertrap" design is presented. The unique criss-crossed fiber structures demonstrate non-linear mechanical response similar to that observed in native tendon. Mechanical testing revealed that optimizing the fiber orientation resulted in the characteristic "S"-shaped curve, demonstrating a toe region and linear elastic region. This project has promising research potential across various disciplines: vascular engineering, nerve regeneration, and ligament and tendon tissue engineering.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.