Evidence map›Paper›PMID 27141437›Full record

ArticleInternational journal for parasitology. Parasites and wildlife2016

Investigation on possible transmission of monkeys' Plasmodium to human in a populations living in the equatorial rainforest of the Democratic republic of Congo.

Dieudonné Makaba Mvumbi, Thierry Lengu Bobanga, Solange Efundu Umesumbu, Billy Shako Kunyu, Jean-Marie Ntumba Kayembe, Nani-Tuma H Situakibanza, Georges Lelo Mvumbi, Pierrette Melin, Patrick De Mol, Marie-Pierre Hayette

Abstract read
In one paragraph

Article in International journal for parasitology. Parasites and wildlife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dieudonné Makaba MvumbiBiochemistry and Molecular Biology Unit, Department of Basic Sciences, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Thierry Lengu BobangaDepartment of Parasitology and Tropical Medicine, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Solange Efundu UmesumbuNational Malaria Control Program, Democratic Republic of Congo.
Billy Shako KunyuDepartment of Parasitology and Tropical Medicine, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Jean-Marie Ntumba KayembeDepartment of Internal Medicine, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Nani-Tuma H SituakibanzaDepartment of Parasitology and Tropical Medicine, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo; Department of Internal Medicine, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Georges Lelo MvumbiBiochemistry and Molecular Biology Unit, Department of Basic Sciences, School of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Pierrette MelinDepartment of Clinical Microbiology, University Hospital of Liège, Liège, Belgium.
Patrick De MolDepartment of Clinical Microbiology, University Hospital of Liège, Liège, Belgium.
Marie-Pierre HayetteDepartment of Clinical Microbiology, University Hospital of Liège, Liège, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized as naturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi. This fifth species, P. knowlesi, previously identified as naturally parasitizing the monkey Macaca fascicularis, has been microscopically confused for a long time with P. malariae or P. falciparum and it was not possible to correctly differentiate them until the advent of molecular biology. To date, natural human infections with P. knowlesi only occur in Southeast Asia and a similar phenomenon of natural transmission of simian plasmodium to humans has not been reported elsewhere. This study was conducted to investigate a possible transmission of African small monkey's plasmodium to humans in populations living near the rainforest of the Democratic Republic of Congo (DRC) where several species of non-human primates are living. Two successive real-time PCRs were identified in the literature and used in combination for purpose. Only P. falciparum was found in this study. However, studies with larger samples and with more advanced techniques should be conducted.

Indexed as

Democratic Republic of CongoMalariaMonkey plasmodiumRT-PCR

Identifiers

PMID27141437
PMCPMC4840266

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.