Evidence map›Paper›PMID 27141393›Full record

ArticleOncoimmunology2016

The controversial role of TNF in melanoma.

Marco Donia, Julie Westerlin Kjeldsen, Inge Marie Svane

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Integration of transcriptomics data into agent-based models of solid tumor metastasis.Computational and structural biotechnology journal · 2023
    Article
  4. Article
  5. Article
  6. Repurposing approved drugs for cancer therapy.British medical bulletin · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness.Journal of experimental & clinical cancer research : CR · 2018
    Article
  12. Immunoplasticity in cutaneous melanoma: beyond pure morphology.Virchows Archiv : an international journal of pathology · 2017
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marco DoniaCenter for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
Julie Westerlin KjeldsenCenter for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen , Herlev, Denmark.
Inge Marie SvaneCenter for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
Herlev Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TNF has been associated with both inhibition and promotion of tumor growth. We recently described a mechanism by which tumor cells attract TNF producing cells via expression of MHC class II molecules.

Indexed as

Antitumor CD4 T cell responses; Melanoma; tumor immune escape; Tumor necrosis factor (TNF)- MHC class II

Identifiers

PMID27141393
PMCPMC4839341
OpenAlexW2326548474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.