Evidence map›Paper›PMID 27141314›Full record

ArticleEuropean journal of microbiology & immunology2016

Influence of Toxoplasma Gondii Infection on Symptoms and Signs of Menopause.

Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Edwin Adiel Calzada-Torres, Sergio Estrada-Martínez, Alma Rosa Pérez-Álamos, Raquel Vaquera-Enriquez, Arturo Díaz-Herrera, Raúl Segura-Moreno, María de Lourdes Guerrero-Carbajal and 4 more

Abstract read
In one paragraph

Article in European journal of microbiology & immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects of diet and ovariectomy onBrain communications · 2025
    Article
  2. Influence ofEuropean journal of microbiology & immunology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cosme Alvarado-EsquivelFaculty of Medicine and Nutrition, Juárez University of Durango State , Avenida Universidad S/N, 34000 Durango, Dgo, Mexico.
Luis Francisco Sánchez-AnguianoInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State . Avenida Universidad S/N, 34000 Durango, Durango, Mexico.
Jesús Hernández-TinocoInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State . Avenida Universidad S/N, 34000 Durango, Durango, Mexico.
Edwin Adiel Calzada-TorresFacultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico.
Sergio Estrada-MartínezInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State . Avenida Universidad S/N, 34000 Durango, Durango, Mexico.
Alma Rosa Pérez-ÁlamosInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State . Avenida Universidad S/N, 34000 Durango, Durango, Mexico.
Raquel Vaquera-EnriquezHealth Center No. 2 "Dr. Carlos Santamaría", Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
Arturo Díaz-HerreraHealth Center No. 2 "Dr. Carlos Santamaría", Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
Raúl Segura-MorenoHealth Center No. 2 "Dr. Carlos Santamaría", Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
María de Lourdes Guerrero-CarbajalHealth Center No. 2 "Dr. Carlos Santamaría", Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
María Guadalupe Rentería-LópezHealth Center No. 2 "Dr. Carlos Santamaría", Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
Isabel Beristain GarcíaFacultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico.
Elizabeth Rábago-SánchezFaculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Dgo, Mexico; General Hospital, Secretary of Health, Avenida 5 de febrero 220, 34000 Durango, Mexico.
Oliver LiesenfeldInstitute for Microbiology and Hygiene, Campus Benjamin Franklin, Charité Medical School , Hindenburgdamm 27, D-12203 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some symptoms of menopause have also been described in patients with toxoplasmosis. Whether Toxoplasma gondii (T. gondii) infection has any influence on clinical manifestations of menopause is yet unknown. We sought to determine whether T. gondii exposure is associated with symptoms and signs of menopause. We performed a cross-sectional study of women attending a public health center in Durango City, Mexico. Participants were examined for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays. A questionnaire including 47 symptoms and signs potentially associated with menopause was applied. Association of seroprevalence for T. gondii with clinical characteristics of women was assessed by bivariate and multivariate analyses. Bivariate analysis showed that bouts of rapid heartbeat, breast pain, electric shock sensation, dizziness, digestive problems, low back pain, and migraine were associated with seropositivity to either IgG anti-T. gondii alone or both IgG and IgM anti-T. gondii. Breast pain was the only variable that was found to be associated with IgG seropositivity to T. gondii by multivariate analysis: (OR = 2.84; 95% CI: 1.35-5.90; P = 0.005). Our results suggest that T. gondii exposure may influence on the clinical manifestations of menopause. Results deserve further research.

Indexed as

cross-sectional studymenopauseperimenopauseseroprevalenceToxoplasma gondii

Identifiers

PMID27141314
PMCPMC4838985

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.