ArticleHypertension (Dallas, Tex. : 1979)2016
Ethnic Differences in and Childhood Influences on Early Adult Pulse Wave Velocity: The Determinants of Adolescent, Now Young Adult, Social Wellbeing, and Health Longitudinal Study.
Article in Hypertension (Dallas, Tex. : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Childhood Risk Factors and Adulthood Cardiovascular Disease: A Systematic Review.The Journal of pediatrics · 2021Pooled it
- When the sum isn't the whole - The vascular status score and its components in hypertension identification: The African PREDICT study.Journal of human hypertension · 2026Article
- Role of Ethnicity and Sex in Hypertension-Mediated Organ Damage in a Dual-Ethnic Cohort of Individuals With Hypertension.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Arterial Stiffness and Central Hemodynamics in South Asian, African American, and White Adolescents and Young Adults-The Charisma Study.American journal of hypertension · 2026Article
- Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships.Reviews in cardiovascular medicine · 2025Review
- Discrimination, religious affiliation, and arterial stiffness in African American women and men.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Association between perceived discrimination and pulse wave velocity: a scoping review.BMJ public health · 2024Article
- Relationship between objectively measured physical activity and subclinical cardiovascular disease: a systematic review.BMJ open sport & exercise medicine · 2024Article
- Central and local arterial stiffness in White Europeans compared to age-, sex-, and BMI-matched South Asians.PloS one · 2023Article
- Arterial Stiffness and HbA1c: Association Mediated by Insulin Resistance in Hispanic Adults.International journal of environmental research and public health · 2022Article
- Arterial stiffness and atrial fibrillation: A review.Clinics (Sao Paulo, Brazil) · 2022Review
- Racial differences of early vascular aging in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2021Review
- Antihypertensive Medication Use and Its Effects on Blood Pressure and Haemodynamics in a Tri-ethnic Population Cohort: Southall and Brent Revisited (SABRE).Frontiers in cardiovascular medicine · 2021Article
- Ethnic differences in subclinical vascular function in South Asians, Whites, and African Americans in the United States.International journal of cardiology. Heart & vasculature · 2020Article
- Aortic pulse wave velocity in individuals of Asian and African ancestry: the HELISUR study.Journal of human hypertension · 2020Article
- Association of pulse wave velocity and intima-media thickness with cardiovascular risk factors in young adults.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Arterial stiffness and hypertension status in Afro-Caribbean men.Journal of hypertension · 2019Article
- Brief Report: Physical Activity, Body Mass Index and Arterial Stiffness in Children with Autism Spectrum Disorder: Preliminary Findings.Journal of autism and developmental disorders · 2018Article
- Feasibility and characteristics of arterial stiffness measurement in preschool children.European journal of preventive cardiology · 2017Article
- Longitudinal study of the influence of lung function on vascular health from adolescence to early adulthood in a British multiethnic cohort.Journal of hypertension · 2017Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
Early determinants of aortic stiffness as pulse wave velocity are poorly understood. We tested how factors measured twice previously in childhood in a multiethnic cohort study, particularly body mass, blood pressure, and objectively assessed physical activity affected aortic stiffness in young adults. Of 6643 London children, aged 11 to 13 years, from 51 schools in samples stratified by 6 ethnic groups with different cardiovascular risk, 4785 (72%) were seen again at aged 14 to 16 years. In 2013, 666 (97% of invited) took part in a young adult (21-23 years) pilot follow-up. With psychosocial and anthropometric measures, aortic stiffness and blood pressure were recorded via an upper arm calibrated Arteriograph device. In a subsample (n=334), physical activity was measured >5 days via the ActivPal. Unadjusted pulse wave velocities in black Caribbean and white UK young men were similar (mean±SD 7.9±0.3 versus 7.6±0.4 m/s) and lower in other groups at similar systolic pressures (120 mm Hg) and body mass (24.6 kg/m(2)). In fully adjusted regression models, independent of pressure effects, black Caribbean (higher body mass/waists), black African, and Indian young women had lower stiffness (by 0.5-0.8; 95% confidence interval, 0.1-1.1 m/s) than did white British women (6.9±0.2 m/s). Values were separately increased by age, pressure, powerful impacts from waist/height, time spent sedentary, and a reported racism effect (+0.3 m/s). Time walking at >100 steps/min was associated with reduced stiffness (P<0.01). Effects of childhood waist/hip were detected. By young adulthood, increased waist/height ratios, lower physical activity, blood pressure, and psychosocial variables (eg, perceived racism) independently increase arterial stiffness, effects likely to increase with age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.