ArticleProceedings of the National Academy of Sciences of the United States of America2016
Coordinated beating of algal flagella is mediated by basal coupling.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed, 189 citations in OpenAlex.
- Heme-binding protein CYB5D1 couples intraflagellar redox to calcium signaling for coordinated flagellar beating.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Light-dependent processes in algae across scales: from cellular physiology to ecological organization.Plant physiology · 2026Review
- Comparative Proteomics of Plasma and Flagellar Membranes inInternational journal of molecular sciences · 2026Article
- Embodied behavioural complexity in a ciliated microorganism.Nature communications · 2026Article
- A mechanical model for a system of coupled elastic filaments for terrestrial robot locomotion.Mathematics and mechanics of solids : MMS · 2026Article
- Dynamics and emergence of metachronal waves in the ciliary band of a metazoan larva.Science advances · 2025Article
- Article
- Light-dependent switching between two flagellar beating states selects versatile phototaxis strategies in microswimmers.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Physical mechanism reveals bacterial slowdown above a critical number of flagella.Journal of the Royal Society, Interface · 2024Article
- Flow Physics Guides Morphology of Ciliated Organs.Nature physics · 2024Article
- Data-driven classification of individual cells by their non-Markovian motion.Biophysical journal · 2024Article
- The younger flagellum sets the beat foreLife · 2024Article
- Swimming ability and flagellar motility of sperm packets of the volvocine green alga Pleodorina starrii.PloS one · 2024Article
- Biohybrid Microalgae Robots: Design, Fabrication, Materials, and Applications.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Perspectives on Principles of Cellular Behavior from the Biophysics of Protists.Integrative and comparative biology · 2023Review
- Article
- Active oscillations in microscale navigation.Animal cognition · 2023Review
- Emerging roles for diguanylate cyclase during the evolution of soma in dictyostelia.BMC ecology and evolution · 2023Article
- Nonreciprocal interactions give rise to fast cilium synchronization in finite systems.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Robust acoustic trapping and perturbation of single-cell microswimmers illuminate three-dimensional swimming and ciliary coordination.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cilia and flagella often exhibit synchronized behavior; this includes phase locking, as seen in Chlamydomonas, and metachronal wave formation in the respiratory cilia of higher organisms. Since the observations by Gray and Rothschild of phase synchrony of nearby swimming spermatozoa, it has been a working hypothesis that synchrony arises from hydrodynamic interactions between beating filaments. Recent work on the dynamics of physically separated pairs of flagella isolated from the multicellular alga Volvox has shown that hydrodynamic coupling alone is sufficient to produce synchrony. However, the situation is more complex in unicellular organisms bearing few flagella. We show that flagella of Chlamydomonas mutants deficient in filamentary connections between basal bodies display markedly different synchronization from the wild type. We perform micromanipulation on configurations of flagella and conclude that a mechanism, internal to the cell, must provide an additional flagellar coupling. In naturally occurring species with 4, 8, or even 16 flagella, we find diverse symmetries of basal body positioning and of the flagellar apparatus that are coincident with specific gaits of flagellar actuation, suggesting that it is a competition between intracellular coupling and hydrodynamic interactions that ultimately determines the precise form of flagellar coordination in unicellular algae.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.