Evidence map›Paper›PMID 27139901›Full record

ReviewPediatric nephrology (Berlin, Germany)2017

Vesicoureteral reflux and the extracellular matrix connection.

Fatima Tokhmafshan, Patrick D Brophy, Rasheed A Gbadegesin, Indra R Gupta

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Children with vesicoureteric reflux have joint hypermobility and occasional tenascin XB sequence variants.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020
    Article
  5. Article
  6. Tenascin-X-Discovery and Early Research.Frontiers in immunology · 2020
    Review
  7. Article
  8. Review
  9. Physiopathology of vesico-ureteral reflux.Italian journal of pediatrics · 2016
    Review
  10. Ureterovesical Junction and Waldeyer's Sheath: A Narrative Review Applied to Vesicoureteral Reflux.International braz j urol : official journal of the Brazilian Society of Urology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Fatima TokhmafshanDepartment of Human Genetics, McGill University, Montreal, QC, Canada.
Patrick D BrophyDepartment of Pediatrics, University of Iowa, Carver College of Medicine, Iowa City, IA, 52242, USA.
Rasheed A GbadegesinDepartment of Pediatrics, Division of Nephrology, Duke University Medical Center, Durham, NC, 27710, USA.
Indra R GuptaDepartment of Human Genetics, McGill University, Montreal, QC, Canada. indra.gupta@muhc.mcgill.ca.
McGill University · CADuke Medical Center · USUniversity of Iowa · US

Funding

IDENTIFICATION OF VUR GENES BY COMBINED LINKAGE ANALYSIS AND EXOME SEQUENCINGR21DK096200 · NIDDK · DUKE UNIVERSITY · PI GBADEGESIN, RASHEED ADEBAYO · 2013 to 2014
$429k
NIDDK NIH HHS R21 DK096200
6 · The paper itself

Abstract

Primary vesicoureteral reflux (VUR) is a common pediatric condition due to a developmental defect in the ureterovesical junction. The prevalence of VUR among individuals with connective tissue disorders, as well as the importance of the ureter and bladder wall musculature for the anti-reflux mechanism, suggest that defects in the extracellular matrix (ECM) within the ureterovesical junction may result in VUR. This review will discuss the function of the smooth muscle and its supporting ECM microenvironment with respect to VUR, and explore the association of VUR with mutations in ECM-related genes.

Indexed as

ChildExtracellular MatrixHumansVesico-Ureteral RefluxCollagenCutis laxaEhlers–Danlos syndromeElastinJoint hypermobilityMarfan syndromeTenascin-XBUreterovesical junctionVesicoureteral refluxWilliams syndrome

Identifiers

PMID27139901
PMCPMC5376290
OpenAlexW2345445911

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.