Evidence map›Paper›PMID 27139454›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Epidemiological Aspects of Blastocystis Colonization in Children in Ilero, Nigeria.

Casper S Poulsen, Akinwale M Efunshile, Jenna A Nelson, Christen R Stensvold

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Trial
  2. Review
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  5. Review
  6. AnthropogenicMicroorganisms · 2025
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  10. Effect ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
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  11. Article
  12. Subtype Distribution ofMicroorganisms · 2024
    Article
  13. Article
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  15. Article
  16. Epidemiology ofPathogens (Basel, Switzerland) · 2023
    Review
  17. Circulation and colonisation ofEpidemiology and infection · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Casper S PoulsenLaboratory of Parasitology, Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark.
Akinwale M EfunshileInstitute of Medical Microbiology and Infectious Disease Epidemiology, Faculty of Medicine, University of Leipzig, Leipzig, Germany. Department of Medical Microbiology, Ebonyi State University, Abakaliki, Nigeria.
Jenna A NelsonDepartment of Public Health Studies, Elon University, Elon, North Carolina.
Christen R StensvoldLaboratory of Parasitology, Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark. run@ssi.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to elucidate aspects of the epidemiology of Blastocystis in Nigerian school children, including the distribution of subtypes (STs) and ST alleles. A total of 199 genomic DNAs extracted from fecal samples from 199 Nigerian children aged 2-14 years were tested by real-time polymerase chain reaction for Blastocystis Positive DNAs were submitted to barcoding by PCR and sequencing to obtain information on STs and ST alleles. A total of 167 (84%) samples were positive for Blastocystis, with prevalence increasing by age. No association between Blastocystis colonization and gender (P = 0.51) or type/presence of toilet facilities (P = 0.21) was observed. Blastocystis carriers were more prone to using water collected from wells than from sachets (P = 0.0044). Moreover, Blastocystis positivity was associated with positivity for fecal-orally transmitted protozoa (P = 0.018) and helminths (P < 0.0001). A clear inverse association of Blastocystis colonization and malaria infection was observed (P < 0.0001); however, malaria-positive children being younger than malaria-negative children, this finding was attributed to the age effect of Blastocystis colonization. ST data were available for 127/167 (76%) samples. Fifty-one children were positive for ST1, while 42 and 33 children were colonized with ST2 and ST3, respectively; a single case of ST7 was observed. By and large, the ST alleles identified for ST1 and ST2 did not differ from those observed in humans in other regions of the world; meanwhile, the distribution of ST3 alleles was remarkably distinct and potentially specific to humans in sub-Saharan Africa.

Indexed as

AdolescentAfrica South of the SaharaAge FactorsAllelesBlastocystisBlastocystis InfectionsChildChild, PreschoolCohort StudiesDNA, ProtozoanFecesFemaleGenomicsHumansMaleNigeriaDNA, Protozoan

Identifiers

PMID27139454
PMCPMC4944538

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.