ArticlePLoS neglected tropical diseases2016
Prevalence of River Epilepsy in the Orientale Province in the Democratic Republic of the Congo.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Nodding syndrome, a case-control study in Mahenge, Tanzania: Onchocerca volvulus and not Mansonella perstans as a risk factor.PLoS neglected tropical diseases · 2023Article
- Ivermectin treatment response in two rural villages with a high prevalence of onchocerciasis and epilepsy, Mahenge Tanzania.African health sciences · 2022Article
- No Evidence Known Viruses Play a Role in the Pathogenesis of Onchocerciasis-Associated Epilepsy. An Explorative Metagenomic Case-Control Study.Pathogens (Basel, Switzerland) · 2021Article
- Onchocerca volvulus and epilepsy: A comprehensive review using the Bradford Hill criteria for causation.PLoS neglected tropical diseases · 2021Review
- Zoonotic Implications ofPathogens (Basel, Switzerland) · 2020Review
- Zoonotic and vector-borne parasites and epilepsy in low-income and middle-income countries.Nature reviews. Neurology · 2020Review
- Low ivermectin use among 5- to 6-year-old children: observations from door-to-door surveys in onchocerciasis-endemic regions in Africa.International health · 2020Article
- Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density.PLoS neglected tropical diseases · 2019Article
- Onchocerciasis-associated epilepsy: another piece in the puzzle from the Mahenge mountains, southern Tanzania.Infectious diseases of poverty · 2019Article
- Stigma and epilepsy in onchocerciasis-endemic regions in Africa: a review and recommendations from the onchocerciasis-associated epilepsy working group.Infectious diseases of poverty · 2019Review
- High prevalence of epilepsy in an onchocerciasis endemic health zone in the Democratic Republic of the Congo, despite 14 years of community-directed treatment with ivermectin: A mixed-method assessment.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019Article
- Article
- Onchocerciasis-Associated Epilepsy with Head Nodding Seizures-Nodding Syndrome: A Case Series of 15 Patients from Western Uganda, 1994.The American journal of tropical medicine and hygiene · 2018Article
- Onchocerca volvulus as a risk factor for developing epilepsy in onchocerciasis endemic regions in the Democratic Republic of Congo: a case control study.Infectious diseases of poverty · 2018Article
- Burden of onchocerciasis-associated epilepsy: first estimates and research priorities.Infectious diseases of poverty · 2018Review
- High prevalence of epilepsy in onchocerciasis endemic health areas in Democratic Republic of the Congo.Infectious diseases of poverty · 2018Article
- High prevalence of epilepsy in two rural onchocerciasis endemic villages in the Mahenge area, Tanzania, after 20 years of community directed treatment with ivermectin.Infectious diseases of poverty · 2018Article
- High prevalence of epilepsy in onchocerciasis endemic regions in the Democratic Republic of the Congo.PLoS neglected tropical diseases · 2017Article
- Onchocerciasis-associated epilepsy: From recent epidemiological and clinical findings to policy implications.Epilepsia open · 2017Review
- Risk factors for epilepsy in Bas-Uélé Province, Democratic Republic of the Congo: a case-control study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2016Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn increased prevalence of epilepsy has been reported in many onchocerciasis endemic areas.
objectiveTo determine the prevalence and distribution of epilepsy in an onchocerciasis endemic region in the Democratic Republic of the Congo (DRC). DESIGN/
methodsAn epilepsy prevalence study was carried out in 2014, in two localities of the Bas-Uélé district, an onchocerciasis endemic region in the Orientale Province of the DRC. Risk factors for epilepsy were identified using a random effects logistic regression model and the distribution of epilepsy cases was investigated using the Moran's I statistic of spatial auto-correlation.
resultsAmong the 12,776 individuals of Dingila, 373 (2.9%) individuals with epilepsy were identified. In a house-to-house survey in Titule, 68 (2.3%) of the 2,908 people who participated in the survey were found to present episodes of epilepsy. Epilepsy showed a marked spatial pattern with clustering of cases occurring within and between adjacent households. Individual risk of epilepsy was found to be associated with living close to the nearest fast flowing river where blackflies (Diptera: Simuliidae)-the vector of Onchocerca volvulus-oviposit and breed.
conclusionsThe prevalence of epilepsy in villages in the Bas-Uélé district in the DRC was higher than in non-onchocerciasis endemic regions in Africa. Living close to a blackflies infested river was found to be a risk factor for epilepsy.
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