ReviewCurrent drug abuse reviews2016
The Impact of Marijuana Use on Memory in HIV-Infected Patients: A Comprehensive Review of the HIV and Marijuana Literatures.
Review in Current drug abuse reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07414459 (Combining Social Network Strategies and Routine Substance Use Screening), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combining Social Network Strategies and Routine Substance Use Screening
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The Association Between Marijuana Use and HIV Continuum of Care Outcomes: a Systematic Review.Current HIV/AIDS reports · 2019Pooled it
- Impact of cannabis use on white matter hyperintensities in adults with and without chronic HIV disease.Journal of neurovirology · 2026Article
- Neural compensation in persons with HIV and marijuana use: Insights from a reorganized DMN.Network neuroscience (Cambridge, Mass.) · 2026Article
- Tobacco and Cannabis Co-use by HIV Status Among United States Adults: Results from the 2021-2023 National Survey on Drug Use and Health.AIDS and behavior · 2025Article
- Joint effects of human immunodeficiency virus (HIV) and cannabis on neurocognition.Neuropsychology · 2025Article
- Changes in frequency of cannabis use among people with HIV during the COVID-19 pandemic: a multi-methods study to explore the underlying reasons for change.The American journal of drug and alcohol abuse · 2023Article
- Article
- Marijuana Use and Health Outcomes in Persons Living With HIV: Protocol for the Marijuana Associated Planning and Long-term Effects (MAPLE) Longitudinal Cohort Study.JMIR research protocols · 2022Article
- Central Nervous System Impact of Perinatally Acquired HIV in Adolescents and Adults: an Update.Current HIV/AIDS reports · 2022Review
- Cannabidiol modulates expression of type I IFN response genes and HIV infection in macrophages.Frontiers in immunology · 2022Article
- Sexual behaviors, cannabis, alcohol and monkeypox infection.Frontiers in public health · 2022Review
- HIV Transgenic Rats Demonstrate Impaired Sensorimotor Gating But Are Insensitive to Cannabinoid (Δ9-Tetrahydrocannabinol)-Induced Deficits.The international journal of neuropsychopharmacology · 2021Article
- Cannabis and Alcohol Co-Use and Condomless Anal Sex Among Men Who have Sex with Men Living with HIV: An Event-Level Analysis.AIDS and behavior · 2021Article
- Resting-State Directional Connectivity and Anxiety and Depression Symptoms in Adult Cannabis Users.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- Synergistic effects of HIV and marijuana use on functional brain network organization.Progress in neuro-psychopharmacology & biological psychiatry · 2021Article
- Reciprocal Influences of HIV and Cannabinoids on the Brain and Cognitive Function.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020Review
- Cannabis Exposure is Associated With a Lower Likelihood of Neurocognitive Impairment in People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- A Systematic Review of the Neurocognitive Effects of Cannabis Use in Older Adults.Current addiction reports · 2019Article
- Cannabis Consumption in People Living with HIV: Reasons for Use, Secondary Effects, and Opportunities for Health Education.Cannabis and cannabinoid research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe most robust neurocognitive effect of marijuana use is memory impairment. Memory deficits are also high among persons living with HIV/AIDS, and marijuana is the most commonly used drug in this population. Yet research examining neurocognitive outcomes resulting from co-occurring marijuana and HIV is limited.
objectiveThe primary objectives of this comprehensive review are to: (1) examine the literature on memory functioning in HIV-infected individuals; (2) examine the literature on memory functioning in marijuana users; (3) synthesize findings and propose a theoretical framework to guide future research.
methodPubMed was searched for English publications 2000-2013. Twenty-two studies met inclusion criteria in the HIV literature, and 23 studies in the marijuana literature.
resultsAmong HIV-infected individuals, memory deficits with medium to large effect sizes were observed. Marijuana users also demonstrated memory problems, but results were less consistent due to the diversity of samples.
conclusionA compensatory hypothesis, based on the cognitive aging literature, is proposed to provide a framework to explore the interaction between marijuana and HIV. There is some evidence that individuals infected with HIV recruit additional brain regions during memory tasks to compensate for HIV-related declines in neurocognitive functioning. Marijuana is associated with disturbance in similar brain systems, and thus it is hypothesized that the added neural strain of marijuana can exhaust neural resources, resulting in pronounced memory impairment. It will be important to test this hypothesis empirically, and future research priorities are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.