ArticlePloS one2016
Change in Health-Related Quality of Life among Pulmonary Tuberculosis Patients at Primary Health Care Settings in South Africa: A Prospective Cohort Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and associated factors for alcohol use disorder among tuberculosis patients: a systematic review and meta-analysis study.Substance abuse treatment, prevention, and policy · 2021Pooled it
- Article
- Quality of life among people with tuberculosis in the Eastern Cape, South Africa: a qualitative study.BMC global and public health · 2026Article
- Health related quality of life of tuberculosis patients in South India: A longitudinal assessment study.PloS one · 2025Article
- Effects of extrapulmonary TB on patient quality of life and recurrence.Public health action · 2024Article
- Factors affecting the readiness for hospital discharge of initially treated pulmonary tuberculosis patients in China: a phenomenological study.BMC public health · 2024Article
- Health-related quality of life among adults newly diagnosed with pulmonary tuberculosis in Lagos State, Nigeria: a prospective study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- PPE59 antibodies in tuberculous patients and potential use for diagnosis when assayed with other rapid biomarkers.Memorias do Instituto Oswaldo Cruz · 2024Article
- The Impact of Chronic Pulmonary Aspergillosis Co-infection on the Health-Related Quality of Life of Patients with Pulmonary Tuberculosis in Uganda.Mycopathologia · 2023Article
- The Impact of Chronic Pulmonary Aspergillosis Co-infection on the Health-Related Quality of Life of Patients with Pulmonary Tuberculosis in Uganda.Research square · 2023Article
- A randomized controlled trial to evaluate the impact of pharmacist-led clinical interventions on the health-related quality of life among TB patients.Frontiers in pharmacology · 2023Article
- Functioning Problems Associated with Health Conditions with Greatest Disease Burden in South Africa: A Scoping Review.International journal of environmental research and public health · 2022Article
- Health-Related Quality of Life (HRQoL) of Patients with Tuberculosis: A Review.Infectious disease reports · 2022Review
- Prednisone for the prevention of tuberculosis-associated IRIS (randomized controlled trial): Impact on the health-related quality of life.Frontiers in psychology · 2022Article
- Quality of life and associated factors among patients with tuberculosis at the University of Gondar comprehensive specialized hospital, Ethiopia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Health-Related Quality of Life in Tuberculosis Patients in Eritrea: Comparison Among Drug-Susceptible and Rifampicin/Multidrug-Resistant Tuberculosis Patients.Patient related outcome measures · 2021Article
- Comorbidities between tuberculosis and common mental disorders: a scoping review of epidemiological patterns and person-centred care interventions from low-to-middle income and BRICS countries.Infectious diseases of poverty · 2020Article
- Factors Affecting Tuberculosis Patients' Quality of Life in Surabaya, Indonesia.Journal of multidisciplinary healthcare · 2020Article
- Quality of life with tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2019Review
- Effect of DOTS on quality of life among tuberculosis patients: A follow-up study in a health district of Kolkata.Journal of family medicine and primary care · 2019Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
introductionPulmonary tuberculosis (TB) remains a major public health challenge in South Africa. However, little attention is paid to the impact of health related quality of life (HRQL) among TB patients at the beginning and at the end of TB treatment. This study assesses factors associated with HRQL among tuberculosis patients in three high risk provinces in South Africa.
methodsA prospective cohort study was conducted at primary health care settings. Patients completed the HRQL social functioning (SF)-12 health survey. Comparison of Physical Health Summary Score (PCS) and Mental Health Summary Score (MCS) was assessed at 6 months after treatment. Generalized estimating equations (GEEs) were used to examine the factors associated with changes in HRQL.
resultsIn all patients, after 6 months of treatment there was a significant improvement in HRQL with the biggest increase in the PCS. A higher educational qualification had a strong significant positive effect on the mental HRQL. Psychological distress showed a significant negative association with physical and mental HRQL after six months. Permanent residence showed a significant positive association with mental HRQL among TB patients compared to those living in shack/traditional dwellings. Rating ones health as being good and fair/poor was significantly associated with poor physical HRQL. Twenty drinks or more in the past month had a significant negative effect on the physical HRQL.
conclusionThe findings suggest that programmes targeted at improving TB treatment success should have specific interventions for patients with low educational background, impoverished households/communities and those with hazardous or harmful alcohol use.
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