Evidence map›Paper›PMID 27137207›Full record

ArticleTechniques in coloproctology2016

Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy.

Y Thorsen, B Stimec, S N Andersen, J C Lindstrom, F Pfeffer, T Oresland, D Ignjatovic, RCC study group

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 7 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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  6. Systematic review: the effect of right hemicolectomy for cancer on postoperative bowel function.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Y ThorsenDepartment of Digestive Surgery, Akershus University Hospital, University of Oslo, Lorenskog, Norway.
B StimecAnatomy Sector, Department of Cellular Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
S N AndersenDepartment of Pathology, Akershus University Hospital, University of Oslo, Lorenskog, Norway.
J C LindstromHelse Sør-Øst Health Services Research Center, Akershus University Hospital, Lorenskog, Norway.
F PfefferDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
T OreslandDepartment of Digestive Surgery, Akershus University Hospital, University of Oslo, Lorenskog, Norway.
D IgnjatovicDepartment of Digestive Surgery, Akershus University Hospital, University of Oslo, Lorenskog, Norway. dexexer01@hotmail.com.
RCC study group
University of Oslo · NOAkershus University Hospital · NOUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: "Safe Radical D3 Right Hemicolectomy for Cancer through Preoperative Biphasic Multi-detector Computed Tomography" in which all soft tissue surrounding the superior mesenteric vessels from the level of the middle colic artery to that of the ileocolic artery was removed.

methodsBowel function and gastrointestinal quality of life in two consecutive cohorts that underwent right colectomy with and without D3 extended mesenterectomy were compared. Main outcome measures were the Diarrhea Assessment Scale (DAS) and Gastrointestinal Quality of Life Index (GIQLI). The data were collected prospectively through telephone interviews.

resultsForty-nine patients per group, comparable for age, sex, length of bowel resected but with significantly shorter follow-up time in the experimental group, were included. There was no difference in total DAS scores, subscores or additional questions except for higher bowel frequency scores in the D3 group (p = 0.02). Comparison of total GIQLI scores and subscales showed no difference between groups. Regression analysis with correction for confounding factors showed 0.48 lower bowel frequency scores in the D2 group (p = 0.022). Within the D3 group presence of jejunal arteries cranial to the D3 dissection area showed 1.78 lower DAS scores and 0.7 lower bowel frequency scores.

conclusionsSmall bowel denervation after right colectomy with D3 extended mesenterectomy leads to increased bowel frequency but does not impact gastrointestinal quality of life. Individual anatomical variants can affect postoperative bowel function differently despite standardized surgery.

Indexed as

Quality of LifeAdultAgedAutonomic PathwaysColectomyColonic NeoplasmsDefecationDiarrheaFemaleHumansIntestine, LargeIntestine, SmallLymph Node ExcisionMaleMesenteric Artery, SuperiorMesenteric VeinsBowel motilityColorectal cancerMesenterectomyRight hemicolectomySuperior mesenteric plexus

Identifiers

PMID27137207
OpenAlexW2346093449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.