ArticlePsychopharmacology2016
Go and NoGo: modulation of electrophysiological correlates by female sex steroid hormones.
Article in Psychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Impaired inhibition after delta-9-tetrahydrocannabinol in women not related to circulating estradiol levels.Pharmacology, biochemistry, and behavior · 2023Trial
- Assessing the Spectrum of Internet Use in a Healthy Sample: Altered Psychological States and Intact Brain Responses to an Equiprobable Go/NoGo Task.Behavioral sciences (Basel, Switzerland) · 2025Article
- Sex differences in learning and performing the Go/NoGo tasks.Biology of sex differences · 2023Article
- Sex differences in equiprobable auditory Go/NoGo task: effects on N2 and P3.Experimental brain research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleThe behavioral and electrophysiological responses in a Go/NoGo task are objective measures of executive functioning that may be impaired in clinical conditions. Prior to the wider application of Go/NoGo tasks in clinics, it is tempting to evaluate factors causing modulation of the responses.
objectiveWe aimed to evaluate the effect of different levels of female sex steroids on Go/NoGo task-related ERPs in healthy females.
methodsThirty-four young healthy females performed an equiprobable (50/50) auditory Go/NoGo task. Amplitudes and latencies of N2 and P3 peaks from Fz, Cz, and Pz electrodes were evaluated. 17β-estradiol and progesterone levels in saliva samples were measured. Electrophysiological measures were correlated to 17β-estradiol and progesterone concentrations.
resultsThe diverse pattern of modulation of P3 latencies was shown: higher levels of 17β-estradiol contributed to Go-P3 latency prolongation, and higher levels of progesterone contributed to NoGo-P3 latency shortening. Higher levels of 17β-estradiol were associated with more negative frontal N2 amplitude in both conditions.
conclusionsThe relationship between electrophysiological correlates of executive functioning to individual hormonal levels points to a broader range of variation sources in healthy subjects which might mask or pronounce between-group differences in clinical studies.
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Registered trials
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