Evidence map›Paper›PMID 27136589›Full record

ArticleJournal of personalized medicine2016

Barriers and Facilitators to Adoption of Genomic Services for Colorectal Care within the Veterans Health Administration.

Nina R Sperber, Sara M Andrews, Corrine I Voils, Gregory L Green, Dawn Provenzale, Sara Knight

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Delivering genomic medicine in the United Kingdom National Health Service: a systematic review and narrative synthesis.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Pooled it
  2. Trial
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  8. The composition and capacity of the clinical genetics workforce in high-income countries: a scoping review.Genetics in medicine : official journal of the American College of Medical Genetics · 2020
    Article
  9. Integrating Germline Genetics Into Precision Oncology Practice in the Veterans Health Administration: Challenges and Opportunities.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nina R SperberCenter for Health Services Research in Primary Care, Health Services Research & Development Service, 411 West Chapel Hill Street, Suite 600, Durham, NC 27701, USA. nina.sperber@va.gov.
Sara M AndrewsCenter for Health Services Research in Primary Care, Health Services Research & Development Service, 411 West Chapel Hill Street, Suite 600, Durham, NC 27701, USA. Sara.Andrews@va.gov.
Corrine I VoilsCenter for Health Services Research in Primary Care, Health Services Research & Development Service, 411 West Chapel Hill Street, Suite 600, Durham, NC 27701, USA. corrine.voils@dm.duke.edu.
Gregory L GreenVAMC, 4150 Clement Street, San Francisco, CA 94121, USA. gregory.green@va.gov.
Dawn ProvenzaleDepartment of Veterans Affairs, Cooperative Studies Program Epidemiology Center, 411 West Chapel Hill Street, Suite 600, Durham, NC 27701, USA. dawn.provenzale@va.gov.
Sara KnightHealth Services Research & Development Service, 700 S. 19th Street, Birmingham, AL 35233, USA. sara.knight@va.gov.
Duke University · USHealth Services Research & Development · USSan Francisco VA Medical Center · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined facilitators and barriers to adoption of genomic services for colorectal care, one of the first genomic medicine applications, within the Veterans Health Administration to shed light on areas for practice change. We conducted semi-structured interviews with 58 clinicians to understand use of the following genomic services for colorectal care: family health history documentation, molecular and genetic testing, and genetic counseling. Data collection and analysis were informed by two conceptual frameworks, the Greenhalgh Diffusion of Innovation and Andersen Behavioral Model, to allow for concurrent examination of both access and innovation factors. Specialists were more likely than primary care clinicians to obtain family history to investigate hereditary colorectal cancer (CRC), but with limited detail; clinicians suggested templates to facilitate retrieval and documentation of family history according to guidelines. Clinicians identified advantage of molecular tumor analysis prior to genetic testing, but tumor testing was infrequently used due to perceived low disease burden. Support from genetic counselors was regarded as facilitative for considering hereditary basis of CRC diagnosis, but there was variability in awareness of and access to this expertise. Our data suggest the need for tools and policies to establish and disseminate well-defined processes for accessing services and adhering to guidelines.

Indexed as

implementation researchLynch syndromequalitative methods

Identifiers

PMID27136589
PMCPMC4932463
OpenAlexW2343355629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.