Evidence map›Paper›PMID 27136498›Full record

Trial reportPsychosomatic medicine2016

Efficacy of Cognitive Behavioral Therapy for Insomnia in Older Adults With Occult Sleep-Disordered Breathing.

Constance H Fung, Jennifer L Martin, Karen Josephson, Lavinia Fiorentino, Joseph M Dzierzewski, Stella Jouldjian, Juan Carlos Rodriguez Tapia, Michael N Mitchell, Cathy Alessi

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychosomatic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02027558 (Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02027558 nacompletednot on this map

Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2014 to 2018Enrolled125ConditionsInsomnia, ApneaArmsInsomnia treatment & PAP adherence, General sleep education
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Sleep Deficiency in Obstructive Sleep Apnea.Sleep medicine clinics · 2024
    Review
  8. Review
  9. Sleep Deficiency in Obstructive Sleep Apnea.Clinics in chest medicine · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Recent Developments in the Management of Insomnia in Later Life.Current treatment options in psychiatry · 2018
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Constance H FungFrom the Geriatric Research, Education and Clinical Center (Fung, Martin, Josephson, Dzierzewski, Jouldjian, Rodriguez, Mitchell, Alessi), VA Greater Los Angeles Healthcare System, Los Angeles, California; Department of Medicine (Fung, Martin, Dzierzewski, Rodriguez, Alessi), David Geffen School of Medicine at UCLA, Los Angeles, California; School of Medicine (Fiorentino), University of California, San Diego, California; and Department of Medicine (Rodriguez), Pontificia Universidad Catolica de Chile, Santiago, Región Metropolitana, Chile.
Jennifer L Martin
Karen Josephson
Lavinia Fiorentino
Joseph M Dzierzewski
Stella Jouldjian
Juan Carlos Rodriguez Tapia
Michael N Mitchell
Cathy Alessi
Geriatric Research Education and Clinical Center · USCommittee on Publication Ethics · GBUniversity of California, San Diego · USVA Greater Los Angeles Healthcare System · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REUBEN, DAVID B. · 2006 to 2017
$9.8M
Improving Older Adults' Decision Making For Obstructive Sleep Apnea TreatmentK23AG045937 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FUNG, CONSTANCE · 2013 to 2017
$786k
NCATS NIH HHS UL1 TR000124NIA NIH HHS K23 AG045937NIA NIH HHS P30 AG028748
6 · The paper itself

Abstract

objectivesThe aims of the study were to determine whether mild, occult sleep-disordered breathing (SDB) moderates the efficacy of cognitive behavioral therapy for insomnia (CBTI) in older adults and to explore whether CBTI reduces the number of patients eligible for positive airway pressure (PAP) therapy.

methodsData were analyzed for 134 adults 60 years or older with insomnia and apnea-hypopnea index (AHI) of less than 15 who were randomized to a larger study of CBTI versus a sleep education control. Sleep outcomes (sleep onset latency, total wake time, wake after sleep onset, sleep efficiency, Pittsburgh Sleep Quality Index) were compared between CBTI and control at 6 months using repeated-measures analysis of variance adjusted for baseline values. AHI of 5 or greater versus less than 5 was included as an interaction term to evaluate changes in sleep outcomes. The number of participants at baseline and 6 months with mild SDB for whom insomnia was their only other indication for PAP was also compared between CBTI and control.

resultsAHI status (AHI ≥ 5 [75.5% of participants] versus AHI < 5) did not moderate improvements in sleep associated with CBTI (all p values ≥ .12). Nine (45.0%) of 20 participants with mild SDB for whom insomnia was their only other indication for PAP therapy at baseline no longer had another indication for PAP at 6 months, with no significant difference between CBTI and control.

conclusionsCBTI improves sleep in older veterans with insomnia and untreated mild SDB. Larger trials are needed to assess whether CBTI reduces the number of patients with mild SDB eligible for PAP.

Indexed as

Outcome Assessment, Health CareAgedAged, 80 and overCognitive Behavioral TherapyContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedSleep Apnea SyndromesSleep Initiation and Maintenance DisordersVeterans

Identifiers

PMID27136498
PMCPMC4891271
OpenAlexW2344963125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.