Evidence map›Paper›PMID 27136467›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

White blood cell counts and neutrophil to lymphocyte ratio in the diagnosis of testicular cancer: a simple secondary serum tumor marker.

Ozgur Haki Yuksel, Ayhan Verit, Aytac Sahin, Ahmet Urkmez, Fatih Uruc

Open access · diamondAbstract read
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Diagnostic and prognostic role of NLR in testicular cancer.Exploration of targeted anti-tumor therapy · 2024
    Pooled it
  2. Comparison of inflammation-based biomarkers in metastatic testicular cancer at initial diagnosis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
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  16. Can routine peripheral blood counts like neutrophil-to-lymphocyte ratio be beneficial in prediagnosis of testicular cancer and its stages?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
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  20. The relationship of neutrophil to lymphocyte ratio with testicular cancer.International braz j urol : official journal of the Brazilian Society of Urology
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ozgur Haki YukselDepartment of Urology, Fatih Sultan Mehmet Research & Training Hospital, Istanbul, Turkey.
Ayhan VeritDepartment of Urology, Fatih Sultan Mehmet Research & Training Hospital, Istanbul, Turkey.
Aytac SahinDepartment of Urology, Fatih Sultan Mehmet Research & Training Hospital, Istanbul, Turkey.
Ahmet UrkmezDepartment of Urology, Fatih Sultan Mehmet Research & Training Hospital, Istanbul, Turkey.
Fatih UrucDepartment of Urology, Fatih Sultan Mehmet Research & Training Hospital, Istanbul, Turkey.
Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the study was to investigate white blood cell counts and neutrophil to lymphocyte ratio (NLR) as markers of systemic inflammation in the diagnosis of localized testicular cancer as a malignancy with initially low volume. MATERIALS AND

methodsThirty-six patients with localized testicular cancer with a mean age of 34.22±14.89 years and 36 healthy controls with a mean age of 26.67±2.89 years were enrolled in the study. White blood cell counts and NLR were calculated from complete blood cell counts.

resultsWhite blood cell counts and NLR were statistically significantly higher in patients with testicular cancer compared with the control group (p<0.0001 for all).

conclusionsBoth white blood cell counts and NLR can be used as a simple test in the diagnosis of testicular cancer besides the well-known accurate serum tumor markers as AFP (alpha fetoprotein), hCG (human chorionic gonadotropin) and LDH (lactate dehydrogenase).

Indexed as

LymphocytesNeutrophilsAdultBiomarkers, TumorCase-Control StudiesHemoglobinsHumansLymphocyte CountMaleMiddle AgedNeoplasms, Germ Cell and EmbryonalPrognosisReference ValuesReproducibility of ResultsRetrospective StudiesROC CurveBiomarkers, TumorHemoglobins

Identifiers

PMID27136467
PMCPMC4811226
OpenAlexW2330603087

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.