Evidence map›Paper›PMID 27136433›Full record

ReviewBlood transfusion = Trasfusione del sangue2016

How we treat bleeding associated with direct oral anticoagulants.

Giuseppe Marano, Stefania Vaglio, Simonetta Pupella, Giancarlo M Liumbruno, Massimo Franchini

Open access · greenAbstract readReview
In one paragraph

Review in Blood transfusion = Trasfusione del sangue, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Management of Coagulopathy in Bleeding Patients.Journal of clinical medicine · 2021
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giuseppe MaranoItalian National Blood Centre, National Institute of Health, Rome, Italy.
Stefania VaglioItalian National Blood Centre, National Institute of Health, Rome, Italy.
Simonetta PupellaItalian National Blood Centre, National Institute of Health, Rome, Italy.
Giancarlo M LiumbrunoItalian National Blood Centre, National Institute of Health, Rome, Italy.
Massimo FranchiniDepartment of Transfusion Medicine and Haematology, "Carlo Poma" Hospital, Mantua, Italy.
Azienda Ospedaliera Carlo Poma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the case of bleeding or emergency situations such as trauma, stroke requiring thrombolysis, and urgent surgery. The progressive development of antidotes for these new drugs, which, it is hoped, will become available in the near future, will allow better and safer management of the rapid reversal of their anticoagulant effect.

Indexed as

Administration, OralAnticoagulantsAntidotesHemorrhageHumansStrokeThromboembolismAnticoagulantsAntidotes

Identifiers

PMID27136433
PMCPMC5016308
OpenAlexW2345737790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.