Evidence map›Paper›PMID 27136429›Full record

ReviewBlood transfusion = Trasfusione del sangue2016

Is solvent/detergent plasma better than standard fresh-frozen plasma? A systematic review and an expert consensus document.

Marco Marietta, Massimo Franchini, M Lucia Bindi, Francesco Picardi, Matteo Ruggeri, Giustina De Silvestro

Open access · greenAbstract readReview
In one paragraph

Review in Blood transfusion = Trasfusione del sangue, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Emergency Blood Transfusion for Trauma and Perioperative Resuscitation: Standard of Care.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
    Review
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marco MariettaDepartment of Oncology, Haematology and Respiratory Diseases, University Hospital, Modena, Italy.
Massimo FranchiniDepartment of Haematology and Transfusion Medicine, "Carlo Poma" Hospital, Mantua, Italy.
M Lucia BindiLiver Transplant Anaesthesia and Critical Care Medicine, University Hospital "Nuovo Santa Chiara", Pisa, Italy.
Francesco PicardiImmunohaematology and Transfusion Medicine Service, "S. Salvatore" Hospital, Pesaro, Italy.
Matteo RuggeriPostgraduate School of Health Economics and Management (Altems) and Istitute of Economic Policy, Catholic University of the Sacred Hearth, Roma, Italy.
Giustina De SilvestroImmunohaematology and Transfusion Medicine, University Hospital, Padua, Italy.
Azienda Ospedaliera Carlo Poma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnly a few studies have compared solvent/detergent plasma (SD-plasma) to standard fresh-frozen plasma (FFP) in terms of efficacy and safety. MATERIALS AND

methodsA systematic review was performed in order to develop a consensus document on the use of SD-plasma. Moreover, a pharmacoeconomic study was performed in order to assess whether the use of SD-plasma can be cost-effective with respect to the use of FFP. A multidisciplinary panel used the systematic review and the GRADE methodology to develop evidence-based recommendations on this topic.

resultsBased on moderate to very low quality evidence, the panel developed the following consensus statements: (i) the panel suggested that SD-plasma is safer than FFP; (ii) the panel could not express for or against a greater efficacy of SD-plasma as compared to FFP; (iii) the panel suggested that in patients undergoing liver transplantation SD-plasma can be preferred over FFP; (iv) the panel suggested that SD-plasma can be preferred over FFP in patients with thrombotic thrombocytopenic purpura undergoing plasma-exchange procedures; (v) the panel could not recommend for or against preferring SD-plasma over FFP in critical care patients; and (vi) the panel suggested that the use of SD-plasma can be cost-effective with respect to the use of FFP. DISCUSSION: Data from additional randomised studies are needed to establish more definitive guidelines on the use of SD-plasma.

Identifiers

PMID27136429
PMCPMC4942317
OpenAlexW2411542775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.