Evidence map›Paper›PMID 27135575›Full record

ArticleThe Science of the total environment2016

Provision of well-water treatment units to 600 households in Bangladesh: A longitudinal analysis of urinary arsenic indicates fading utility.

Tiffany R Sanchez, Diane Levy, Mohammad Hasan Shahriar, Mohammad Nasir Uddin, Abu B Siddique, Joseph H Graziano, Angela Lomax-Luu, Alexander van Geen, Mary V Gamble

Abstract read
In one paragraph

Article in The Science of the total environment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tiffany R SanchezDepartment of Environmental Health Sciences, Columbia University, 722 West 168th St. Floor 11, New York, NY 10032, United States. Electronic address: trs2111@cumc.columbia.edu.
Diane LevyDepartment of Biostatistics, Columbia University, 722 West 168th St. Floor 8, New York, NY 10032, United States. Electronic address: dl2015@cumc.columbia.edu.
Mohammad Hasan ShahriarColumbia University Bangladesh Research Project, Dhaka, Bangladesh. Electronic address: shahriar@urb-bd.org.
Mohammad Nasir UddinColumbia University Bangladesh Research Project, Dhaka, Bangladesh. Electronic address: nasirbmb@gmail.com.
Abu B SiddiqueColumbia University Bangladesh Research Project, Dhaka, Bangladesh. Electronic address: suman_siddiq@yahoo.com.
Joseph H GrazianoDepartment of Environmental Health Sciences, Columbia University, 722 West 168th St. Floor 11, New York, NY 10032, United States. Electronic address: jg24@cumc.columbia.edu.
Angela Lomax-LuuDepartment of Environmental Health Sciences, Columbia University, 722 West 168th St. Floor 11, New York, NY 10032, United States. Electronic address: aml2221@cumc.columbia.edu.
Alexander van GeenDepartment of Geochemistry, Lamont-Doherty Earth Observatory, 131 Comer. 61 Route 9W, PO Box 1000, Palisades, NY 10964, United States. Electronic address: avangeen@ldeo.columbia.edu.
Mary V GambleDepartment of Environmental Health Sciences, Columbia University, 722 West 168th St. Floor 11, New York, NY 10032, United States. Electronic address: mvg7@cumc.columbia.edu.
Columbia University · USLamont-Doherty Earth Observatory · US

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Diane Berengere Re · 1998 to 2026
$44.7M
Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood ArenicR01CA133595 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2009 to 2013
$2.3M
Biomarkers for Arsenic Toxicity: Genetics, Epigenetics and FolateR01ES017875 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2010 to 2013
$1.9M
Building Capacity to Reduce Arsenicosis in BangladeshD43TW005724 · FIC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GRAZIANO, JOSEPH H · 2001 to 2011
$1.8M
Nutrients involved 1-carbon metabolism and the methylation of arsenic and DNAR00ES018890 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HALL, MEGAN NINA · 2012 to 2014
$731k
FIC NIH HHS D43 TW005724NCI NIH HHS R01 CA133595NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P42 ES010349NIEHS NIH HHS R00 ES018890NIEHS NIH HHS R01 ES017875
6 · The paper itself

Abstract

backgroundMillions of villagers in Bangladesh remain exposed to high levels of arsenic (As) from drinking untreated well-water even though the scale of the problem was recognized 15years ago. Water treatment at the household-level has been promoted as a viable complement but few longitudinal studies of their efficacy using an objective measure of exposure have been conducted. Participants (N=622) of a nutrition trial in Araihazar, Bangladesh were each provided with READ-F filters at the beginning of the study and encouraged to use them over the 6month duration of the intervention. Well-water As, treated water As, and urinary As were monitored periodically during the trial and measured again one year after the trial ended.

resultsThe READ-F filters were initially well received and median urinary As levels for participants declined from 117μg/L to 51μg/L within a single week. However, median urinary As levels gradually rose back to 126μg/L by the end of the trial. Fifty filters were replaced over the course of the trial because of insufficient As removal or reduced flow. With these exceptions, most of the treated water met the WHO guideline for As in drinking water of 10μg/L. One year after the nutritional trial ended, 95% of participants had abandoned their filter citing inconvenience as the primary reason. At that time, median urinary As levels for 10 participants who had switched to a nearby low-As well had declined to 63μg/L.

conclusionsParticipants were probably no longer using the READ-F filter long before the 6month nutritional intervention ended despite claiming that they were using them. Household-level treatment is likely to continue to play a minor role in the effort to reduce As exposure in Bangladesh. Understanding the limitations of such expensive interventions is important for future policy regarding As mitigation.

Indexed as

AdultArsenicBangladeshDrinking WaterFamily CharacteristicsFemaleHumansMaleMiddle AgedWater Pollutants, ChemicalWater PurificationWater SupplyYoung AdultArsenicDrinking WaterWater Pollutants, ChemicalArsenicBiomarkerGroundwaterLongitudinal studyTreatmentWater filters

Identifiers

PMID27135575
PMCPMC4907796
OpenAlexW2344467541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.