ArticlePlants (Basel, Switzerland)2014
Vacuolar Na⁺/H⁺ NHX-Type Antiporters Are Required for Cellular K⁺ Homeostasis, Microtubule Organization and Directional Root Growth.
Article in Plants (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- The Halophyte SpeciesPlants (Basel, Switzerland) · 2022Article
- Auxin Homeostasis and Distribution of the Auxin Efflux Carrier PIN2 Require Vacuolar NHX-Type Cation/HPlants (Basel, Switzerland) · 2020Article
- Genetic localization of the SPC gene controlling pod coiling direction in Medicago truncatula.Genes & genomics · 2020Article
- Function of NHX-type transporters in improving rice tolerance to aluminum stress and soil acidity.Planta · 2020Article
- Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/HFrontiers in plant science · 2020Review
- Expressing class I wheat NHX (TaNHX2) gene in eggplant (Solanum melongena L.) improves plant performance under saline condition.Functional & integrative genomics · 2019Article
- Cation Specificity of Vacuolar NHX-Type Cation/HPlant physiology · 2019Article
- Antarctic Extremophiles: Biotechnological Alternative to Crop Productivity in Saline Soils.Frontiers in bioengineering and biotechnology · 2019Article
- KPlant physiology · 2018Article
- Auxin Contributes to the Intraorgan Regulation of Gene Expression in Response to Shade.Plant physiology · 2018Article
- Transcriptomic analysis reveals vacuolar NaBMC plant biology · 2018Article
- Two NHX-type transporters from Helianthus tuberosus improve the tolerance of rice to salinity and nutrient deficiency stress.Plant biotechnology journal · 2018Article
- Enhanced Growth Performance and Salinity Tolerance in Transgenic Switchgrass via Overexpressing Vacuolar NaFrontiers in plant science · 2017Article
- Root-endophytes improve the ecophysiological performance and production of an agricultural species under drought condition.AoB PLANTS · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Na⁺/H⁺ antiporters (NHXs) are integral membrane transporters that catalyze the electroneutral exchange of K⁺ or Na⁺ for H⁺ and are implicated in cell expansion, development, pH and ion homeostasis and salt tolerance. Arabidopsis contains four vacuolar NHX isoforms (NHX1-NHX4), but only the functional roles for NHX1 and NHX2 have been assessed thus far. Colocalization studies indicated that NHX3 and NHX4 colocalize to the tonoplast. To investigate the role of all vacuolar NHX isoforms, a quadruple knockout nhx1nhx2nhx3nhx4, lacking all vacuolar NHXs, was generated. Seedlings of nhx1nhx2nhx3nhx4 displayed significantly reduced growth, with markedly shorter hypocotyls. Under high K⁺, but not Na⁺, pronounced root skewing occurred in nhx1nhx2nhx3nhx4, suggesting that the organization of the cytoskeleton might be perturbed. Whole mount immunolabeling of cortical microtubules indicated that high K⁺ caused significant microtubule reorganization in nhx1nhx2nhx3nhx4 root cells of the elongation zone. Using microtubule stabilizing (Taxol) and destabilizing (propyzamide) drugs, we found that the effect of K⁺ on nhx1nhx2nhx3nhx4 root growth was antagonistic to that of Taxol, whereas elevated K⁺ exacerbated the endogenous effect of propyzamide on root skewing. Collectively, our results suggest that altered K⁺ homeostasis leads to an increase in the dynamics of cortical microtubule reorganization in nhx1nhx2nhx3nhx4 root epidermal cells of the elongation zone.
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