SynthesisPloS one2016
A Systematic Review of Cognitive Behavioral Therapy and Behavioral Activation Apps for Depression.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06442774 (Digital Tool to Improve Maternal Mental Health), which is not on this map. Cited by 144 papers, 15 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Digital Tool to Improve Maternal Mental Health: Enhancing Well-being, Early Detection, Diagnosis Support, and Monitoring of Mental Health Problems During the Perinatal Period
Who cites it
144 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- Evaluating Characteristics and Quality of Mental Health Apps Available in App Stores for Indian Users: Systematic App Search and Review.JMIR mHealth and uHealth · 2025Pooled it
- Could the use of web-based applications assist in neuropsychiatric treatment? An umbrella review.BMC psychology · 2025Pooled it
- Bibliometric analysis of trends, innovations, and the future of CBT-based mobile interventions for depression.Frontiers in medicine · 2025Pooled it
- Revealing the evolution of behavioral activation research trends over two decades through keyword network analysis.PloS one · 2025Pooled it
- Pooled it
- Scope, Characteristics, Behavior Change Techniques, and Quality of Conversational Agents for Mental Health and Well-Being: Systematic Assessment of Apps.Journal of medical Internet research · 2023Pooled it
- Just-in-Time Adaptive Mechanisms of Popular Mobile Apps for Individuals With Depression: Systematic App Search and Literature Review.Journal of medical Internet research · 2021Pooled it
- Smartphone-Based Interventions and Internalizing Disorders in Youth: Systematic Review and Meta-analysis.Journal of medical Internet research · 2021Pooled it
- Smartphone applications for depression: a systematic literature review and a survey of health care professionals' attitudes towards their use in clinical practice.European archives of psychiatry and clinical neuroscience · 2020Pooled it
- Evaluating Commercially Available Mobile Apps for Depression Self-Management.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Pooled it
- Behavior Change Content, Understandability, and Actionability of Chronic Condition Self-Management Apps Available in France: Systematic Search and Evaluation.JMIR mHealth and uHealth · 2019Pooled it
- Characteristics and quality of genetics and genomics mobile apps: a systematic review.European journal of human genetics : EJHG · 2019Pooled it
- What Works and What Doesn't Work? A Systematic Review of Digital Mental Health Interventions for Depression and Anxiety in Young People.Frontiers in psychiatry · 2019Pooled it
- Pooled it
- Mental Health Mobile Apps for Preadolescents and Adolescents: A Systematic Review.Journal of medical Internet research · 2017Pooled it
- Moderators, mediators, and components of a standalone smartphone application for postpartum depression: secondary analysis of a randomized controlled trial.Archives of women's mental health · 2026Trial
- Assessing the Efficacy of the INTELLECT Cognitive Behavioral Therapy Mobile App for Anxiety and Depressive Symptoms Among At-Risk Japanese Employees: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Engagement, Acceptability, and Effectiveness of the Self-Care and Coach-Supported Versions of the Vira Digital Behavior Change Platform Among Young Adults at Risk for Depression and Obesity: Pilot Randomized Controlled Trial.JMIR mental health · 2024Trial
- Mixed-methods feasibility outcomes for a novel ACT-based video game 'ACTing Minds' to support mental health.BMJ open · 2024Trial
- A Pilot Randomized Controlled Trial to Evaluate a Cognitive Behavioral Videogame Intervention:Games for health journal · 2023Trial
84 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is a common mental health condition for which many mobile apps aim to provide support. This review aims to identify self-help apps available exclusively for people with depression and evaluate those that offer cognitive behavioural therapy (CBT) or behavioural activation (BA). One hundred and seventeen apps have been identified after searching both the scientific literature and the commercial market. 10.26% (n = 12) of these apps identified through our search offer support that seems to be consistent with evidence-based principles of CBT or BA. Taking into account the non existence of effectiveness/efficacy studies, and the low level of adherence to the core ingredients of the CBT/BA models, the utility of these CBT/BA apps are questionable. The usability of reviewed apps is highly variable and they rarely are accompanied by explicit privacy or safety policies. Despite the growing public demand, there is a concerning lack of appropiate CBT or BA apps, especially from a clinical and legal point of view. The application of superior scientific, technological, and legal knowledge is needed to improve the development, testing, and accessibility of apps for people with depression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.