ArticlePlants (Basel, Switzerland)2016
The C2 Protein from the Geminivirus Tomato Yellow Leaf Curl Sardinia Virus Decreases Sensitivity to Jasmonates and Suppresses Jasmonate-Mediated Defences.
Article in Plants (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 52 citations in OpenAlex.
- In silico structural and disorder prediction of the tomato yellow leaf curl virus C2 protein and experimental assessment of subcellular localization and HR-like response.Journal of computer-aided molecular design · 2026Article
- Induced Systemic Resistance in thePlants (Basel, Switzerland) · 2023Article
- Review
- Combinatorial interactions between viral proteins expand the potential functional landscape of the tomato yellow leaf curl virus proteome.PLoS pathogens · 2022Article
- The Ubiquitin-Proteasome System (UPS) and Viral Infection in Plants.Plants (Basel, Switzerland) · 2022Review
- The novel C5 protein from tomato yellow leaf curl virus is a virulence factor and suppressor of gene silencing.Stress biology · 2022Article
- The interplay of plant hormonal pathways and geminiviral proteins: partners in disease development.Virus genes · 2022Review
- Geminiviruses encode additional small proteins with specific subcellular localizations and virulence function.Nature communications · 2021Article
- Targets and Mechanisms of Geminivirus Silencing Suppressor Protein AC2.Frontiers in microbiology · 2021Review
- Review
- Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle.Frontiers in plant science · 2020Review
- Comprehensive molecular insights into the stress response dynamics of rice (Journal of biosciences · 2020Article
- Plant begomoviruses subvert ubiquitination to suppress plant defenses against insect vectors.PLoS pathogens · 2019Article
- The six Tomato yellow leaf curl virus genes expressed individually in tomato induce different levels of plant stress response attenuation.Cell stress & chaperones · 2017Article
- Maintenance of Cotton Leaf Curl Multan Betasatellite byFrontiers in plant science · 2017Article
- Insights Into Virus-Encoded RNA Silencing Suppressors Across Viral Families: A Focus on Viruses Infecting Solanaceae Crops.Physiologia plantarumReview
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing body of evidence points at a role of the plant hormones jasmonates (JAs) in determining the outcome of plant-virus interactions. Geminiviruses, small DNA viruses infecting a wide range of plant species worldwide, encode a multifunctional protein, C2, which is essential for full pathogenicity. The C2 protein has been shown to suppress the JA response, although the current view on the extent of this effect and the underlying molecular mechanisms is incomplete. In this work, we use a combination of exogenous hormone treatments, microarray analysis, and pathogen infections to analyze, in detail, the suppression of the JA response exerted by C2. Our results indicate that C2 specifically affects certain JA-induced responses, namely defence and secondary metabolism, and show that plants expressing C2 are more susceptible to pathogen attack. We propose a model in which C2 might interfere with the JA response at several levels.
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