ArticleMolecular ecology2016
Genomic analysis reveals depression due to both individual and maternal inbreeding in a free-living mammal population.
Article in Molecular ecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 143 citations in OpenAlex.
- Runs of Homozygosity Predict Inbreeding Depression Across Taxa: A Systematic Review and Meta-Analysis.Molecular ecology · 2026Pooled it
- Limited Lifetime Costs of Inbreeding in a Large Wild Population of Superb Fairy-Wrens.Molecular ecology · 2026Article
- Fitness Regulates Non-Native Species Recovery in a Simulated Trojan MEvolutionary applications · 2026Article
- Mothers Matter Most: Maternal, but Not Paternal, Age and Inbreeding Affect Nestling Telomere Length in a Wild Passerine.Molecular ecology · 2026Article
- Genome-Wide Homozygosity Predicts Inbreeding Depression in the Hihi/Stitchbird (Evolutionary applications · 2026Article
- Genomic Architecture of Inbreeding Depression Associated With Hatching Failure in an Endangered Parrot.Molecular ecology · 2026Article
- Parasite-mediated inbreeding depression in wild red deer.Heredity · 2025Article
- Inbreeding Depression Across Multiple Life-History Traits in a Long-Lived Mammal.Molecular ecology · 2025Article
- Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Kin recognition for incest avoidance in Damaraland mole-rats,Proceedings. Biological sciences · 2024Article
- Strongly deleterious mutations influence reproductive output and longevity in an endangered population.Nature communications · 2024Article
- Whole-Genome Analyses Reveal the Distinct Taxonomic Status of the Hainan Population of EndangeredEvolutionary applications · 2024Article
- Effects of inbreeding on reproductive success in endangered North Atlantic right whales.Royal Society open science · 2024Article
- Little evidence of inbreeding depression for birth mass, survival and growth in Antarctic fur seal pups.Scientific reports · 2024Article
- Detecting inbreeding depression in structured populations.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Purifying and balancing selection on embryonic semi-lethal haplotypes in a wild mammal.Evolution letters · 2024Article
- Notes on the conservation threats to the western lesser spot-nosed monkey (Cercopithecus petaurista buettikoferi) in the Bijagós Archipelago (Guinea-Bissau, West Africa).Primates; journal of primatology · 2023Article
- An empirical evaluation of the estimation of inbreeding depression from molecular markers under suboptimal conditions.Evolutionary applications · 2023Article
- Spatial genetic structure of European wild boar, with inferences on late-Pleistocene and Holocene demographic history.Heredity · 2023Article
- A comparison of marker-based estimators of inbreeding and inbreeding depression.Genetics, selection, evolution : GSE · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
There is ample evidence for inbreeding depression manifested as a reduction in fitness or fitness-related traits in the focal individual. In many organisms, fitness is not only affected by genes carried by the individual, but also by genes carried by their parents, for example if receiving parental care. While maternal effects have been described in many systems, the extent to which inbreeding affects fitness directly through the focal individual, or indirectly through the inbreeding coefficients of its parents, has rarely been examined jointly. The Soay sheep study population is an excellent system in which to test for both effects, as lambs receive extended maternal care. Here, we tested for both maternal and individual inbreeding depression in three fitness-related traits (birthweight and weight and hindleg length at 4 months of age) and three fitness components (first-year survival, adult annual survival and annual breeding success), using either pedigree-derived inbreeding or genomic estimators calculated using ~37 000 SNP markers. We found evidence for inbreeding depression in 4-month hindleg and weight, first-year survival in males, and annual survival and breeding success in adults. Maternal inbreeding was found to depress both birthweight and 4-month weight. We detected more instances of significant inbreeding depression using genomic estimators than the pedigree, which is partly explained through the increased sample sizes available. In conclusion, our results highlight that cross-generational inbreeding effects warrant further exploration in species with parental care and that modern genomic tools can be used successfully instead of, or alongside, pedigrees in natural populations.
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