Evidence map›Paper›PMID 27135053›Full record

ArticleACS sensors

Electrochemiluminescent Array to Detect Oxidative Damage in ds-DNA Using [Os(bpy)

Itti Bist, Boya Song, Islam M Mosa, Tia E Keyes, Aaron Martin, Robert J Forster, James F Rusling

Abstract read
In one paragraph

Article in ACS sensors. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Role of mitochondrial DNA in diabetes Mellitus Type I and Type II.Saudi journal of biological sciences · 2022
    Review
  6. Review
  7. The Role of Mitochondrial Mutations and Chronic Inflammation in Diabetes.International journal of molecular sciences · 2021
    Review
  8. Article
  9. 3D-Printed Immunosensor Arrays for Cancer Diagnostics.Sensors (Basel, Switzerland) · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Itti BistDepartment of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States.
Boya SongDepartment of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States.
Islam M MosaDepartment of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States; Department of Chemistry, Tanta University, Tanta 31527, Egypt.
Tia E KeyesSchool of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
Aaron MartinSchool of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
Robert J ForsterSchool of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
James F RuslingDepartment of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States; Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States; School of Chemistry, National University of Ireland, Galway, Ireland; University of Connecticut Health Center, Farmington, Connecticut 06032, United States.
Dublin City University · IEUniversity of Connecticut · USOllscoil na Gaillimhe – University of Galway · IETanta University · EG

Funding

ELECTROCATALYTIC STUDIES OF TOXIC POLLUTANT ACTIVATIONR01ES003154 · NIEHS · UNIVERSITY OF CONNECTICUT STORRS · PI RUSLING, JAMES F. · 1985 to 2018
$6.1M
NIEHS NIH HHS R01 ES003154
6 · The paper itself

Abstract

Reactive oxygen species (ROS) oxidize guanosines in DNA to form 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG), a biomarker for oxidative stress. Herein we describe a novel 64-microwell electrochemiluminescent (ECL) array enabling sensitive multiplexed detection of 8-oxodG in ds-DNA without hydrolysis. Films of Nafion and reduced graphene oxide containing ECL dye [Os(bpy)

Indexed as

DNA oxidation sensorelectrochemiluminescencemicrowell array[Os(bpy)2(phen-benz-COOH)]2+oxidative stress

Identifiers

PMID27135053
PMCPMC4847550
OpenAlexW2261412062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.