Evidence map›Paper›PMID 27134947›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Evaluation of Lipid Profile in Second and Third Trimester of Pregnancy.

Raghuram Pusukuru, Arjun S Shenoi, Prakash Kumar Kyada, Babita Ghodke, Varshil Mehta, Kunal Bhuta, Aadhijaya Bhatia

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03215784 (Impact of Fish Oil or Probiotic Intake on Maternal Obesity and Molecular Biomarkers in the Placenta), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03215784 naunknown statusnot on this map

Impact of Fish Oil or Probiotic Intake on Maternal Obesity and Molecular Biomarkers in the Placenta

TypeinterventionalSponsorUniversidade Federal do Rio de JaneiroRan2015 to 2017Enrolled80ConditionsObesity, Pregnancy, InflammationArmsFish Oil, Probiotic, Placebo
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Maternal Lipids in Pregnancy and Later Life Dyslipidemia: The POUCHmoms Longitudinal Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025
    Article
  7. Lipoprotein(a) throughout life in women.American journal of preventive cardiology · 2024
    Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Correlation of Insulin Resistance in Pregnancy with Obstetric Outcome.Journal of obstetrics and gynaecology of India · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raghuram PusukuruSenior Resident, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Arjun S ShenoiSenior Resident, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Prakash Kumar KyadaSenior Resident, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Babita GhodkeAssociate Professor, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Varshil MehtaIntern, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Kunal BhutaJunior Resident, Department of Medicine, MGM Medical College , Navi Mumbai, India .
Aadhijaya BhatiaJunior Resident, Department of Medicine, MGM Medical College , Navi Mumbai, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is a change in energy usage along with accumulation of fat during different trimesters of pregnancy. Lipid physiology and pathophysiology during pregnancy has not been studied extensively in large population-based cohorts.

aimTo study the levels of total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TGs) during pregnancy and their changes in second and third trimester. MATERIALS AND

methodsThis prospective study was conducted at Mahatma Gandhi Mission Hospital, Navi Mumbai, India by enrolling antenatal cases from October, 2012 to October 2014. The study was conducted on 200 pregnant local women after taking an informed consent from patients to get enrolled in the study. Statistical analyses were performed using Statistical Package for Social Sciences (SPSS) version 17. All reported p-values are two-tailed, and confidence intervals were calculated at the 95% level.

resultsThe mean cholesterol levels in second and third trimester were 214.6±18.16 mg/dl and 242.65±20.44 mg/dl respectively. The mean triglyceride levels in second and third trimester were 188.68±20.88 mg/dl and 216.78±20.09 mg/dl respectively. The mean HDL - Cholesterol levels in second and third trimester were 49.13±6.15 mg/dl and 43.07±4.34 mg/dl respectively. The mean LDL - Cholesterol levels in second and third trimester were 92.41±18.94 mg/dl and 137.82±13.45 mg/dl respectively. The mean VLDL - Cholesterol levels in second and third trimester were 28.22±7.66 mg/dl and 36.27±6.72 mg/dl respectively.

conclusionThis study helps in understanding baseline lipid parameters in the second and third trimester among pregnant women in India. Total Cholesterol, Triglycerides, LDL-Cholesterol, VLDL-Cholesterol increased in both second and third trimester. The increase is more in third trimester, when compared to second. HDL-Cholesterol is decreased in third trimester when compared to second trimester.

Indexed as

Serum cholesterolSerum HDL-cholesterolSerum LDL-cholesterolSerum triglyceridesSerum VLDL-cholesterol

Identifiers

PMID27134947
PMCPMC4843332

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.