Evidence map›Paper›PMID 27134884›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Familial Hepatocellular Carcinoma- First Reported Case from India.

Smita Chandra, Anuradha Kusum, Harish Chandra, Kanika Yadav, Sanjiv Kumar Verma

Abstract readCase Reports
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Hepatocellular Carcinoma in Asia: A Challenging Situation.Euroasian journal of hepato-gastroenterology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Smita ChandraAssociate Professor, Department of Pathology, Himalayan Institute of Medical Sciences , SRHU, Swami Ram Nagar, Doiwala, Dehradun, Uttarakhand, India .
Anuradha KusumProfessor, Department of Pathology, Himalayan Institute of Medical Sciences , SRHU, Swami Ram Nagar, Doiwala, Dehradun, Uttarakhand, India .
Harish ChandraProfessor, Department of Pathology, Himalayan Institute of Medical Sciences , SRHU, Swami Ram Nagar, Doiwala, Dehradun, Uttarakhand, India .
Kanika YadavResident, Department of Pathology, Himalayan Institute of Medical Sciences , SRHU, Swami Ram Nagar, Doiwala, Dehradun, Uttarakhand, India .
Sanjiv Kumar VermaProfessor, Department of Medicine, Himalayan Institute of Medical Sciences , SRHU, Swami Ram Nagar, Doiwala, Dehradun, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial clustering of Hepatocellular Carcinoma (HCC) is commonly observed in various parts of the world including China and Eastern Asia where HBV is endemic while in western world, genetic factors and metabolic disorders may play an important role. In India, HCC is considered to be a rare tumour and till date no case of familial HCC has been reported here. Therefore the present case demonstrates rare occurrence of familial HCC which is being reported for the first time from India on cytology. The case also highlights an unusual feature that it was not associated with any risk factor including HBV, HCV infection, alcoholism, obesity, diabetes or smoking suggesting its independent association with genetic factors. Cytology is uncomplicated diagnostic tool for HCC and may be useful for its early diagnosis. This case also highlights the importance of early surveillance and follow up of blood relatives for every case of HCC so that early diagnosis and management of familial HCC is possible.

Indexed as

Cytologyliver malignancyRisk factors

Identifiers

PMID27134884
PMCPMC4843270

What OpenQuestion holds

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Registered trials

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