Evidence map›Paper›PMID 27134832›Full record

ReviewAnnals of cardiothoracic surgery2016

Systematic review and meta-analysis of uniportal versus multiportal video-assisted thoracoscopic lobectomy for lung cancer.

Christopher G Harris, Rebecca S James, David H Tian, Tristan D Yan, Mathew P Doyle, Diego Gonzalez-Rivas, Christopher Cao

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of cardiothoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04511091 (Studio Osservazionale Retrospettivo Uneventful Vatslobectomy), which is not on this map. Cited by 129 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04511091 completednot on this map

Studio Osservazionale Retrospettivo Uneventful Vatslobectomy: Caratteristiche Cliniche

TypeobservationalSponsorUniversity Hospital of FerraraRan2014 to 2020Enrolled10,000ConditionsThoracic Surgery, Video-AssistedArmsVATS lobectomy
3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Single-Port Robotic-Assisted Approach in Thoracic Surgery: A Prospective Real-World Study.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Intercostal nerve blockJournal of thoracic disease · 2026
    Article
  10. Article
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  14. Review
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  17. Observational
  18. Article
  19. Initial outcomes with uniportal video-assisted lung resection.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher G Harris1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
Rebecca S James1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
David H Tian1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
Tristan D Yan1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
Mathew P Doyle1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
Diego Gonzalez-Rivas1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.
Christopher Cao1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 The Sydney Children's Hospital, Sydney, Australia ; 3 Royal North Shore Hospital, Sydney, Australia ; 4 Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia ; 5 University of Sydney, Sydney, Australia ; 6 Department of Cardiothoracic Surgery, St George Hospital, Sydney, Australia ; 7 Department of Thoracic Surgery (Coruña University Hospital) and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coruña, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUniportal video-assisted thoracoscopic surgery (VATS) has emerged as a less invasive alternative to the conventional multiportal approach in the treatment of lung cancer. The benefits of this uniportal technique have not yet been characterized in patients undergoing VATS lobectomy. This meta-analysis aimed to compare the clinical outcomes of uniportal and multiportal VATS lobectomy for patients with lung cancer.

methodsA systematic review was conducted using seven electronic databases. Endpoints for analysis included perioperative mortality and morbidity, operative time, length of hospital stay, perioperative blood loss, duration of postoperative drainage and rates of conversion to open thoracotomy.

resultsEight relevant observational studies were identified and included for meta-analysis. Results demonstrated a statistically significant reduction in the overall rate of complications, length of hospital stay and duration of postoperative drainage for patients who underwent uniportal VATS lobectomy. There were no significant differences between the two treatment groups in regard to mortality, operative time, perioperative blood loss and rate of conversion to open thoracotomy.

conclusionsThe present meta-analysis demonstrated favourable outcomes for uniportal VATS lobectomy in the treatment of lung cancer compared to the conventional multiportal approach. However, long-term follow-up data is still needed to further characterize the benefits of the uniportal approach.

Indexed as

lobectomylung cancermeta-analysisUniportalvideo-assisted thoracoscopic surgery (VATS)

Identifiers

PMID27134832
PMCPMC4827401

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.