Evidence map›Paper›PMID 27134816›Full record

ArticleCurrent pharmacology reports2016

Natural Agents Used in Chemoprevention of Aerodigestive and GI Cancers.

Jay Morris, Yuan Fang, Keya De Mukhopdhyay, Michael J Wargovich

Open access · bronzeAbstract read
In one paragraph

Article in Current pharmacology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Curcumin: A Potent Protectant against Esophageal and Gastric Disorders.International journal of molecular sciences · 2019
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jay MorrisDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
Yuan FangDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
Keya De MukhopdhyayDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
Michael J WargovichDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
The University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Tea Modulation of Colon CarcinogenesisR01CA096694 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI WARGOVICH, MICHAEL · 2002 to 2014
$2.6M
NCI NIH HHS P30 CA054174NCI NIH HHS R01 CA096694
6 · The paper itself

Abstract

Aerodigestive cancers are on an increasing level in both occurrence and mortality. A major cause in many of these cancers is disruption of the inflammatory pathway, leading to increased cell proliferation, and epigenetic silencing of normal regulatory genes. Here we review the research on several natural products: silibinin, silymarin, quercetin, neem & nimbolide, gingerol, epigallatecatechin-3- gallate, curcumin, genistein and resveratrol conducted on aerodigestive cancers. These types of cancers are primarily those from oral cavity, esophagus/windpipe, stomach, small and large intestine, colon/rectum and bile/pancreas tissues. We report on the utilization

Indexed as

aerodigestive cancerEGCGgenisteinnatural productquercetinresveratrol

Identifiers

PMID27134816
PMCPMC4847748
OpenAlexW2280957128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.