Evidence map›Paper›PMID 27134696›Full record

ArticleThe World Allergy Organization journal2016

Debates in allergy medicine: specific immunotherapy efficiency in children with atopic dermatitis.

Tatiana A Slavyanakaya, Vladislava V Derkach, Revaz I Sepiashvili

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Recent advances in allergen immunotherapy.Chinese medical journal · 2026
    Review
  2. Molecular aspects of allergens in atopic dermatitis.Current opinion in allergy and clinical immunology · 2017
    Review
  3. World Allergy Organization Journal: the Editors Look Back at 2016.The World Allergy Organization journal · 2017
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tatiana A SlavyanakayaPeople's Friendship University of Russia, Moscow, Moscow region Russia ; Institute of Immunophysiology, Moscow, Russia.
Vladislava V DerkachInstitute of Immunophysiology, Moscow, Russia ; Pacific State Medical University, Vladivostok, Russia.
Revaz I SepiashviliPeople's Friendship University of Russia, Moscow, Moscow region Russia ; Institute of Immunophysiology, Moscow, Russia.
Institute of Immunology and Physiology · RUPeoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen specific immunotherapy (AIT) has been the only pathogenetically relevant treatment of IgE-mediated allergic diseases (ADs) for many years. The use of AIT for atopic dermatitis (AD) treatment is dubious and has both followers and opponents. The improvement of subcutaneous AIT (SCIT) and introduction of Sublingual immunotherapy (SLIT) gives prospects of their application both for adults and children suffering from AD. This review presents results of scientific research, system and meta-analyses that confirm the clinical efficacy of AIT for children with AD who has the sensitization to allergens of house dust mite, grass and plant pollen suffering from co-occurring respiratory ADs and with moderate and severe course of allergic AD. There have been analyzed the most advanced achievements in AIT studies as well as there have been specified the unmet needs in AD. The preliminary diagnostics of IgE-mediated AD and pathophysiological disorders, including immune ones, will allow a doctor to develop appropriate comprehensive treatment algorithm for children's AD aimed at its correction. The including of AIT to the children's comprehensive therapy program is reasonable only if AD has the allergic form. It is necessary better to design the randomized research studies and to acquire extended clinical practice in children with AD. Use of the successes of molecular-based allergy diagnostics will help to optimize and personalize the process of selecting the necessary allergens to determine the most appropriate vaccines for children considering the results of the allergen component diagnostics. The strategy of treatment of children with AD in future will be based on individual target therapy.

Indexed as

AeroallergenAllergen specific immunotherapyAtopic dermatitisChildrenClinical efficacySubcutaneous specific immunotherapySublingual specific immunotherapy

Identifiers

PMID27134696
PMCPMC4836162
OpenAlexW2340849941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.