ArticleTherapeutic advances in gastroenterology2016
Fecal microbiota transplant for Clostridium difficile infection in older adults.
Article in Therapeutic advances in gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Intestinal Microbiota in Elderly Inpatients withInfection and drug resistance · 2020Article
- Efficacy of different faecal microbiota transplantation protocols forUnited European gastroenterology journal · 2018Article
- Fecal Transplantation for Treatment of Clostridium Difficile Infection in Elderly and Debilitated Patients.Digestive diseases and sciences · 2018Article
- Therapeutic manipulation of the microbiota: past, present, and considerations for the future.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2016Review
- Early Results of Fecal Microbial Transplantation Protocol Implementation at a Community-based University Hospital.Journal of global infectious diseasesArticle
- Fecal Microbiota Transplantation for the Management ofSurgical infectionsReview
- Adverse events of fecal microbiota transplantation: a meta-analysis of high-quality studies.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundThe objective of this study was to describe the safety of fecal microbiota transplant (FMT) for Clostridium difficile infection (CDI) among older adults.
methodsWe performed a case review of all FMT recipients aged 65 or older treated at Emory University Hospital, a tertiary care and referral center for Georgia and surrounding states.
resultsCDI resolved in 27 (87%) of 31 respondents, including three individuals who received multiple FMTs. Among four whose CDI was not resolved at follow up, three respondents did well initially before CDI recurred, and one individual never eradicated his CDI despite repeating FMT. During the study, five deaths and eight serious adverse events requiring hospitalization were reported within the study group during the follow-up period. Fecal transplant was not a causative factor in these events. The most common adverse event reported in 4 (13%) of 31 respondents was subjective worsening of arthritis.
conclusionFMT is a generally safe and effective treatment option for older adults with CDI.
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Registered trials
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