Evidence map›Paper›PMID 27134599›Full record

ArticleGastroenterology & hepatology2015

Sleep Dysfunction and Gastrointestinal Diseases.

Vikesh Khanijow, Pia Prakash, Helene A Emsellem, Marie L Borum, David B Doman

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Gastroenterology & hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 5 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
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  5. Prevalence of sleep disorder in irritable bowel syndrome: A systematic review with meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  6. Improving Effect of Ellagic Acid on Sleep Quality and Gastrointestinal Symptoms in Patient With Irritable Bowel Syndrome: Randomized Double-Blind Clinical Trial.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Trial
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  14. Eating behaviors and mental health among celiac patients, case-control study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vikesh KhanijowDr Khanijow and Dr Prakash are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Emsellem is a clinical professor of neurology at George Washington University Medical Center and is director of the Center for Sleep and Wake Disorders in Chevy Chase, Maryland. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC and is director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; she is also affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine.
Pia PrakashDr Khanijow and Dr Prakash are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Emsellem is a clinical professor of neurology at George Washington University Medical Center and is director of the Center for Sleep and Wake Disorders in Chevy Chase, Maryland. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC and is director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; she is also affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine.
Helene A EmsellemDr Khanijow and Dr Prakash are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Emsellem is a clinical professor of neurology at George Washington University Medical Center and is director of the Center for Sleep and Wake Disorders in Chevy Chase, Maryland. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC and is director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; she is also affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine.
Marie L BorumDr Khanijow and Dr Prakash are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Emsellem is a clinical professor of neurology at George Washington University Medical Center and is director of the Center for Sleep and Wake Disorders in Chevy Chase, Maryland. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC and is director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; she is also affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine.
David B DomanDr Khanijow and Dr Prakash are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Emsellem is a clinical professor of neurology at George Washington University Medical Center and is director of the Center for Sleep and Wake Disorders in Chevy Chase, Maryland. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC and is director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; she is also affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine.
George Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep deprivation and impaired sleep quality have been associated with poor health outcomes. Many patients experience sleep disturbances, which can increase the risk of medical conditions such as hypertension, obesity, stroke, and heart disease as well as increase overall mortality. Recent studies have suggested that there is a strong association between sleep disturbances and gastrointestinal diseases. Proinflammatory cytokines, such as tumor necrosis factor, interleukin-1, and interleukin-6, have been associated with sleep dysfunction. Alterations in these cytokines have been seen in certain gastrointestinal diseases, such as gastroesophageal reflux disease, inflammatory bowel disease, liver disorders, and colorectal cancer. It is important for gastroenterologists to be aware of the relationship between sleep disorders and gastrointestinal illnesses to ensure good care for patients. This article reviews the current research on the interplay between sleep disorders, immune function, and gastrointestinal diseases.

Indexed as

circadian rhythmcytokinegastrointestinal disordersimmune systemirritable bowel syndromeSleep

Identifiers

PMID27134599
PMCPMC4849511
OpenAlexW2369028609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.