Evidence map›Paper›PMID 27134334›Full record

ArticleDrug development research2001

Actions of a Series of PPADS Analogs at P2X

Sean G Brown, Yong-Chul Kim, Soon-Ai Kim, Kenneth A Jacobson, Geoffrey Burnstock, Brian F King

Open access · greenAbstract read
In one paragraph

Article in Drug development research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The P2X1 receptor as a therapeutic target.Purinergic signalling · 2022
    Review
  6. Review
  7. "Tripartite Synapses" in Taste Buds: A Role for Type I Glial-like Taste Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Purine and pyrimidine (P2) receptors as drug targets.Journal of medicinal chemistry · 2002
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sean G BrownAutonomic Neuroscience Institute, Royal Free and University College Medical School, Hampstead, London, United Kingdom.
Yong-Chul KimMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Soon-Ai KimMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Kenneth A JacobsonMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Geoffrey BurnstockAutonomic Neuroscience Institute, Royal Free and University College Medical School, Hampstead, London, United Kingdom.
Brian F KingAutonomic Neuroscience Institute, Royal Free and University College Medical School, Hampstead, London, United Kingdom.
National Institute of Diabetes and Digestive and Kidney Diseases · USThe Royal Free Hospital · GBUniversity College London · GB

Funding

Development of Drugs Acting at Ion ChannelsZ01DK031127 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 2007 to 2008
$385k
Intramural NIH HHS Z01 DK031127Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

[Table: see text] Seven PPADS (

Indexed as

antagonistATPion channelnucleotideP2X receptorpurinoceptor

Identifiers

PMID27134334
PMCPMC4851439
OpenAlexW2093892864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.