Evidence map›Paper›PMID 27134329›Full record

ArticleAnnual review of gerontology & geriatrics

Resistance Exercise to Prevent and Manage Sarcopenia and Dynapenia.

Timothy D Law, Leatha A Clark, Brian C Clark

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annual review of gerontology & geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 4 syntheses or guidelines pooled it, 182 citations in OpenAlex.

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  18. Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach.International journal of molecular sciences · 2025
    Review
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Timothy D LawOhio Musculoskeletal and Neurological Institute (OMNI), Ohio University, Athens, Ohio; Department of Family Medicine, Ohio University, Athens, Ohio; Department of Geriatric Medicine, Ohio University, Athens, Ohio.
Leatha A ClarkOhio Musculoskeletal and Neurological Institute (OMNI), Ohio University, Athens, Ohio; Department of Family Medicine, Ohio University, Athens, Ohio.
Brian C ClarkOhio Musculoskeletal and Neurological Institute (OMNI), Ohio University, Athens, Ohio; Department of Geriatric Medicine, Ohio University, Athens, Ohio; Department of Biomedical Sciences at Ohio University, Athens, Ohio.
Ohio University · US

Funding

THE RELIEF STUDY: Neuromuscular mechanisms underlying spinal manipulation treatmentsR01AT006978 · NCCIH · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C, THOMAS, JAMES S · 2012 to 2016
$2.1M
Neural mechanisms of dynapeniaR01AG044424 · NIA · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C · 2014 to 2018
$1.4M
Novel Exercise Interventions to Improve Trunk Muscle Function: A Pilot StudyR21AR063909 · NIAMS · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C · 2014 to 2015
$359k
NCCIH NIH HHS R01 AT006978NIAMS NIH HHS R21 AR063909NIA NIH HHS R01 AG044424
6 · The paper itself

Abstract

For well over twenty centuries the muscle wasting (sarcopenia) and weakness (dynapenia) that occurs with old age has been a predominant concern of mankind. Exercise has long been suggested as a treatment to combat sarcopenia and dynapenia, as it exerts effects on both the nervous and muscular systems that are critical to positive physiological and functional adaptations (e.g., enhanced muscle strength). For more than two decades scientists have recognized the profound role that progressive resistance exercise training can have on increasing muscle strength, muscle size and functional capacity in older adults. In this review article we discuss how resistance exercise training can be used in the management and prevention of sarcopenia and dynapenia. We first provide an overview of the evidence for this notion and highlight certain critical factors- namely exercise intensity, volume and progression- that are key to optimizing the resistance exercise prescription. We then highlight how many, if not most, of the commonly prescribed exercise programs for seniors are not the 'best practices', and subsequently present easy-to-read guidelines for a well-rounded resistance exercise training program designed for the management and prevention of sarcopenia and dynapenia, including example training programs for the beginner through the advanced senior resistance exerciser. These guidelines have been written for the academician as well as the student and health care provider across a variety of disciplines, including those in the long term care industry, such as wellness instructors or activity directors.

Indexed as

AgingDynapeniaExerciseMuscleSarcopeniaStrengthWeakness

Identifiers

PMID27134329
PMCPMC4849483
OpenAlexW2428658410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.