Evidence map›Paper›PMID 27134313›Full record

ArticleMikrochimica acta2015

Interference of ATP with the fluorescent probes YOYO-1 andYOYO-3 modifies the mechanical properties of intercalator-stained DNA confined in nanochannels.

Maedeh Roushan, Zubair Azad, Shuang Fang Lim, Hong Wang, Robert Riehn

Open access · greenAbstract read
In one paragraph

Article in Mikrochimica acta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Effects of MgBiochemistry and biophysics reports · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maedeh RoushanDepartment of Physics, NC State University, Raleigh, NC 27695-8202, USA.
Zubair AzadDepartment of Physics, NC State University, Raleigh, NC 27695-8202, USA.
Shuang Fang LimDepartment of Physics, NC State University, Raleigh, NC 27695-8202, USA.
Hong WangDepartment of Physics, NC State University, Raleigh, NC 27695-8202, USA.
Robert RiehnDepartment of Physics, NC State University, Raleigh, NC 27695-8202, USA.
North Central State College · USNorth Carolina State University · US

Funding

Mechanism of protein-mediated looping in a complex environmentR01GM107559 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI RIEHN, ROBERT, WANG, HONG · 2014 to 2017
$1.3M
DNA damage induced structural and dynamic changes at telomeresR00ES016758 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, HONG · 2012 to 2014
$733k
NIEHS NIH HHS R00 ES016758NIGMS NIH HHS R01 GM107559
6 · The paper itself

Abstract

Intercalating fluorescent probes are widely used to visualize DNA in studies on DNA-protein interactions. Some require the presence of adenosine triphosphate (ATP). We have investigated the mechanical properties of DNA stained with the fluorescent intercalating dyes YOYO-1 and YOYO-3 as a function of ATP concentrations (up to 2 mM) by stretching single molecules in nanofluidic channels with a channel cross-section as small as roughly 100×100 nm

Indexed as

ATPDAPIDNAIntercalating dyeNanofluidicsYOYO-1

Identifiers

PMID27134313
PMCPMC4846983
OpenAlexW2083044742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.