Evidence map›Paper›PMID 27133907›Full record

ArticleBrazilian journal of otorhinolaryngology

Quality of life impairment in patients with head and neck cancer and their caregivers: a comparative study.

Laís Rigoni, Raphaella Falco Bruhn, Rafael De Cicco, Jossi Ledo Kanda, Leandro Luongo Matos

Abstract readComparative Study
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Caregiver burden, anxiety, and quality-of-life among informal caregivers of patient with head and neck cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Quality of life of cancer patients at palliative care units in developing countries: systematic review of the published literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Pooled it
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  14. Mandibular rehabilitation: From the Andy Gump deformity to jaw-in-a-day.Laryngoscope investigative otolaryngology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laís RigoniFaculdade de Medicina do ABC, Santo André, SP, Brazil. Electronic address: lais.med44@hotmail.com.
Raphaella Falco BruhnFaculdade de Medicina do ABC, Disciplina de Cirurgia de Cabeça e Pescoço, Santo André, SP, Brazil.
Rafael De CiccoFaculdade de Medicina do ABC, Disciplina de Cirurgia de Cabeça e Pescoço, Santo André, SP, Brazil.
Jossi Ledo KandaFaculdade de Medicina do ABC, Disciplina de Cirurgia de Cabeça e Pescoço, Santo André, SP, Brazil.
Leandro Luongo MatosFaculdade de Medicina do ABC, Disciplina de Saúde Coletiva (Curso de Bioestatística), Santo André, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHead and neck cancer represents 3% of all the types of malignant neoplasms and squamous cell carcinoma (SCC) is responsible for 90% of these cases. There have been some studies evaluating the quality of life of these patients, but little is known about the physical and emotional effects on their caregivers.

objectiveTo evaluate the quality of life of patients with head and neck cancer and their caregivers by applying validated questionnaires.

methodsThirty patients with advanced tumors (SCC stage III or IV) and their 30 caregivers were included. Specific questionnaires (Coop/Wonca, EORTC QLQ-C30, EORTC H&N35, Coop/Wonca, and Caregiver Strain Index - CSI) were applied during routine medical consultations.

resultsOf the 30 patients, 28 were males and 25 had stage IV tumors, with mean age of 56.6 years. 36.7% had the primary tumor in the oropharynx and 70% reported pain. The functional cognitive, physical, and emotional scales were the most affected. Pain, fatigue, and sleep disorders were the most prevalent symptoms. Of the 30 caregivers, 23 were females and 70% were the primary caregivers. 36.7% of the caregivers had high levels of stress, mainly related to the feeling of incapacity. The comparison between patients and caregivers demonstrated that the two groups had similar quality of life impairment: physical fitness (p=0.487), mental health (p=0.615), daily activities (p=0.793), social activities (p=0.301), changes in health (p=0.649), and overall health (p=0.168).

conclusionQuality of life impairment is similar between patients and their caregivers. This result demonstrates that not only the patients show quality of life impairment, but their caregivers also have it and at similar proportions.

Indexed as

AdultAgedAged, 80 and overCarcinoma, Squamous CellCaregiversFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedNeoplasm StagingProspective StudiesQuality of LifeSocioeconomic FactorsSurveys and QuestionnairesCâncer de cabeça e pescoçoCarcinoma espinocelularCaregiversCuidadoresHead and neck cancerQualidade de vidaQuality of lifeSquamous cell carcinoma

Identifiers

PMID27133907
PMCPMC9444724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.