Evidence map›Paper›PMID 27133695›Full record

ArticleClinical imaging

Diffusion tensor imaging in the normal breast: influences of fibroglandular tissue composition and background parenchymal enhancement.

Michael Jonathan Plaza, Elizabeth A Morris, Sunitha B Thakur

Abstract read
In one paragraph

Article in Clinical imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Diffusion-weighted breast MRI: Clinical applications and emerging techniques.Journal of magnetic resonance imaging : JMRI · 2017
    Review
  8. The potential of multiparametric MRI of the breast.The British journal of radiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael Jonathan PlazaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065. Electronic address: Michael.j.plaza@gmail.com.
Elizabeth A MorrisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065. Electronic address: morrise@mskcc.org.
Sunitha B ThakurDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065. Electronic address: thakurs@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveTo evaluate effects of fibroglandular tissue (FGT) composition and background parenchymal enhancement (BPE) on diffusion tensor imaging (DTI) parameters in normal breast tissue.

methodsDTI analysis was performed on 35 breasts with regions of interest drawn to include only normal tissue. Breasts were dichotomized by FGT composition and by BPE; DTI parameters were compared.

resultsThe λ1 principal diffusion coefficient was lower in breasts with moderate/marked BPE versus those with minimal/mild BPE (P=.039). All other parameters were unaffected.

conclusionλ1 is sensitive to differences in BPE within normal breast tissue that should be taken into account in DTI evaluation.

Indexed as

Diffusion Tensor ImagingAdultBreastFemaleHumansMiddle AgedObserver VariationRetrospective StudiesBreastDiffusionDTIMRITensor

Identifiers

PMID27133695
PMCPMC4853756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.