Evidence map›Paper›PMID 27133589›Full record

ArticleJournal of cardiovascular computed tomography

High pitch third generation dual-source CT: Coronary and cardiac visualization on routine chest CT.

Veit Sandfort, Mark A Ahlman, Elizabeth C Jones, Mariana Selwaness, Marcus Y Chen, Les R Folio, David A Bluemke

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular computed tomography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Veit SandfortRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Mark A AhlmanRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Elizabeth C JonesRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Mariana SelwanessRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Marcus Y ChenRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Les R FolioRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
David A BluemkeRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA. Electronic address: bluemked@cc.nih.gov.
National Institutes of Health Clinical Center · US

Funding

Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
Intramural NIH HHS ZIA CL090019Intramural NIH HHS ZIA EB000072
6 · The paper itself

Abstract

backgroundChest CT scans are frequently performed in radiology departments but have not previously contained detailed depiction of cardiac structures.

objectivesTo evaluate myocardial and coronary visualization on high-pitch non-gated CT of the chest using 3rd generation dual-source computed tomography (CT).

methodsCardiac anatomy of patients who had 3rd generation, non-gated high pitch contrast enhanced chest CT and who also had prior conventional (low pitch) chest CT as part of a chest abdomen pelvis exam was evaluated. Cardiac image features were scored by reviewers blinded to diagnosis and pitch. Paired analysis was performed.

results3862 coronary segments and 2220 cardiac structures were evaluated by two readers in 222 CT scans. Most patients (97.2%) had chest CT for oncologic evaluation. The median pitch was 2.34 (IQR 2.05, 2.65) in high pitch and 0.8 (IQR 0.8, 0.8) in low pitch scans (p < 0.001). High pitch CT showed higher image visualization scores for all cardiovascular structures compared with conventional pitch scans (p < 0.0001). Coronary arteries were visualized in 9 coronary segments per exam in high pitch scans versus 2 segments for conventional pitch (p < 0.0001). Radiation exposure was lower in the high pitch group compared with the conventional pitch group (median CTDIvol 10.83 vs. 12.36 mGy and DLP 790 vs. 827 mGycm respectively, p < 0.01 for both) with comparable image noise (p = 0.43).

conclusionMyocardial structure and coronary arteries are frequently visualized on non-gated 3rd generation chest CT. These results raise the question of whether the heart and coronary arteries should be routinely interpreted on routine chest CT that is otherwise obtained for non-cardiac indications.

Indexed as

Incidental FindingsTomography, X-Ray ComputedArtifactsCoronary Artery DiseaseCoronary VesselsEquipment DesignFemaleHeart DiseasesHumansMaleMiddle AgedObserver VariationPredictive Value of TestsRadiation DosageRadiation ExposureRadiography, ThoracicCardiac imagingCTIncidental findings

Identifiers

PMID27133589
PMCPMC4958576
OpenAlexW2336969927

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.