Evidence map›Paper›PMID 27132994›Full record

ArticleExperimental neurology2017

Raphe gene expression changes implicate immune-related functions in ventilatory plasticity following carotid body denervation in rats.

Gary C Mouradian, Pengyuan Liu, Matthew R Hodges

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Methods for the ComprehensiveFrontiers in physiology · 2022
    Article
  3. Perinatal Hypoxemia and Oxygen Sensing.Comprehensive Physiology · 2021
    Article
  4. Article
  5. Acute and chronic changes in the control of breathing in a rat model of bronchopulmonary dysplasia.American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gary C MouradianDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States. Electronic address: gary.mouradian@ucdenver.edu.
Pengyuan LiuDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Matthew R HodgesDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Medical College of Wisconsin · US

Funding

INTEGRATED PHYSIOLOGY TRAINING--MOLECULE TO ORGANISMT32HL007852 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Matthew Robert Hodges · 1996 to 2026
$6.5M
Progressive seizure-induced cardiorespiratory dysfunction in a novel mutant rat model of seizure disorderR01HL122358 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2015 to 2024
$4.3M
Roles of peripheral and central respiratory chemoreceptors in inbred rat strainsR00HL097033 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2011 to 2013
$718k
Roles of peripheral and central respiratory chemoreceptors in inbred rat strainsK99HL097033 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2009 to 2010
$180k
NHLBI NIH HHS K99 HL097033NHLBI NIH HHS R00 HL097033NHLBI NIH HHS R01 HL122358NHLBI NIH HHS T32 HL007852
6 · The paper itself

Abstract

The regulation of blood gases in mammals requires precise feedback mechanisms including chemoreceptor feedback from the carotid bodies. Carotid body denervation (CBD) leads to immediate hypoventilation (increased PaCO

Indexed as

DenervationRespirationAnimalsCarotid BodyDisease Models, AnimalGene Expression RegulationMaleNeuronal PlasticityRaphe NucleiRatsRats, Sprague-DawleyReceptors, GlutamateReceptors, SerotoninRecovery of FunctionRNA, MessengerSerotoninReceptors, GlutamateReceptors, SerotoninRNA, MessengerSerotoninSerotonin Plasma Membrane Transport ProteinsCarotid body denervation (CBD)Medullary rapheNeural control of breathingNeuro-immune responseRespiratory plasticityRNA SequencingSerotonin

Identifiers

PMID27132994
PMCPMC5086315
OpenAlexW2344381182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.